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The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronavirus 2 predict the prognosis of coronavirus disease 2019 pneumonia

https://doi.org/10.1016/j.resinv.2020.12.011Get rights and content

Abstract

The clinical course of coronavirus disease 2019 (COVID-19) varies from mild to critical. We retrospectively examined whether clinical and laboratory findings on admission could predict COVID-19 prognosis. Among various factors associated with COVID-19 severity, our results indicated that the real-time reverse transcription-polymerase chain reaction (RT-PCR) threshold cycle (Ct) values for severe acute respiratory syndrome coronavirus 2 were the most useful predictor of COVID-19 prognosis.

Keywords

COVID-19
SARS-CoV-2
Severity
Prognosis

Abbreviations

COVID-19
coronavirus disease 2019
Ct
threshold cycle
RT-PCR
real time reverse transcription-polymerase chain reaction
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2

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