Elsevier

Schizophrenia Research

Volume 229, March 2021, Pages 46-52
Schizophrenia Research

Induced ideas of reference during social unrest and pandemic in Hong Kong

https://doi.org/10.1016/j.schres.2021.01.027Get rights and content

Abstract

Ideas of reference (IOR) are often implicated in predicting psychosis onset. They have been conceptualized to present on a continuum, from oversensitive psychological reactions to delusional thoughts. It is however unknown to what extent IOR may be triggered by collective environmental stress. We obtained timely data from 9873 individuals to assess IOR in relation to trauma exposure in the 2019–2020 social unrest in Hong Kong. Two levels of IOR are distinguished: attenuated IOR (IOR-A), being the experience of feeling particularly referred to within a group; and exclusive IOR (IOR-E), the experience of feeling exclusively referred to while others are not. Logistic regressions showed that event-based rumination was a shared predictor for IOR-A (OR = 1.07, CI = 1.03–1.10) and IOR-E (OR = 1.09, CI = 1.02–1.17). For IOR-A, three categories of social unrest-related traumatic events (TEs) were significant predictors, including being attacked or having experienced sexual violence (OR = 4.14, CI = 1.93–8.85), being arrested (OR = 4.48, CI = 1.99–10.10), and being verbally abused (OR = 2.66, CI = 1.28–5.53). Being arrested was significant for IOR-E (OR = 3.87, CI = 1.03–14.52), though not when rumination was included. Education level also significantly predicted IOR-E (OR = 0.72, CI = 0.52–0.99). Further analysis revealed that rumination significantly mediated between TEs and IOR severity (β = 0.26, SE = 0.01, CI = 0.24–0.28). The findings are consistent with the hypothesis that IOR-A and IOR-E occur as levels on a continuum, but each has some distinctive correlates. Extrinsic events may play a more prominent role in IOR-A, while intrinsic factors, such as cognitive capacity, may play a more prominent role in IOR-E. The involvement of rumination across the IOR spectrum suggests an opportunity for intervention.

Introduction

Ideas of reference (IOR) can be described as the experience of a spurious sense of relatedness of external events to oneself. IOR are one of the most common groups of symptoms in psychotic disorders, such as schizophrenia (World Health Organization, 1973), and have been observed in a number of other conditions including mood and personality disorders (Colori, 2017; Meyer and Lenzenweger, 2009). Importantly, they also represent prodromal symptoms that may predict psychosis onset (Bendala-Rodríguez et al., 2019). However, little is known concerning whether IOR can be directly triggered by external events, for instance, in the context of large-scale societal conflicts.

Recent studies consider IOR on a psychosis continuum encompassing a range of experiences, from psychologically understandable oversensitivity to self-referential delusions (Rodríguez-Testal et al., 2019; van Os and Reininghaus, 2016). Identifying sets of factors associated with different IOR expressions (corresponding to psychotic-like experiences [PLE], attenuated psychotic symptoms, or psychotic symptoms; Huber and Gross, 1989; Keshavan et al., 2011) may offer insights into how they can emerge in response to intrinsic and extrinsic factors (Bendala-Rodríguez et al., 2019). Past studies have largely viewed IOR as spontaneous experiences linked to individual traits and distant past experiences. While external triggers may play a role in the formation of IOR, their relationships are typically difficult to demonstrate because of the highly individualized and varied contexts associated with spontaneous IOR in everyday life. Shared community stressors may enable investigation into factors associated with IOR induced by well-characterized external events.

Since June 2019, Hong Kong has been undergoing a period of ongoing social unrest. What began as peaceful demonstrations escalated into police-civilian confrontations. Tear gas, rubber bullets, and batons were used for crowd dispersal, while road-blocking and damages to targeted facilities were adopted by some protesters. Over 8000 arrests have been made during this period (Arranz, 2020). Widespread monitoring and surveillance of social media activities have also led to dismissals from jobs and doxxing (for individuals with differing political orientations). During the initial months, substantial levels of mental distress, specifically post-traumatic stress disorder (PTSD) and depressive symptoms, have already been observed (Ni et al., 2020). While societal conflicts remained unresolved, the city was further confronted with waves of coronavirus disease 2019 (COVID-19) outbreak. A recent study has suggested significant increases in PTSD and depressive symptoms as a result of the social unrest, COVID-19, and personal stressful life events (SLEs) in Hong Kong (Wong et al., 2020). Further examination of how these external stressors relate to IOR experiences during ongoing societal conflict and public health crisis would be important.

In studying IOR in a context of societal conflicts, how threat is perceived in an understandable manner may change with events that take place within the community. In this study, we therefore adopted a more stringent criterion for IOR which considers “recipient specificity” as previously described (Wong et al., 2012). We conceptualized recipient specificity as the extent to which an experience is spuriously appraised by the individual as pointing at oneself in particular and to the exclusion of others.

Accordingly, on the milder end of the spectrum, the IOR experiences would involve considering oneself as being particularly referred to more than others, while acknowledging that others are also addressed to a lesser degree, i.e., attenuated IOR (IOR-A). At the other end of the spectrum, a more intense self-referential phenomenon may be less “understandable” and experienced as one being solely and exclusively addressed (i.e., “this [the population-level event] is directed at me and no one else”). The latter of the two, which we term exclusive IOR (IOR-E), would show more resemblance to the aberrant thinking styles encountered in pre-psychotic at-risk mental states (Allswede et al., 2020).

We hypothesized that (1) IOR-A and IOR-E would share some correlates of stressors and vulnerability factors; (2) external social unrest-related traumatic events (TEs) would contribute relatively more to IOR-A and less to IOR-E; (3) rumination, being a transdiagnostic predictor, would be associated with both IOR-A and IOR-E; and (4) individual cognitive functioning, as an intrinsic factor reflected by education level, would be more related to IOR-E.

Section snippets

Participants

This study analyzed data from an online mental health survey collected between February 21, 2020 and March 6, 2020. The survey was developed after in-depth discussions and pilot testing with members of the local community and mental health professionals to ensure relevance and acceptability.

During the data collection period, 20,740 individuals who utilized an Internet-based tool for PTSD and depressive symptom screening and mental health education were invited to participate in a further

Sample characteristics

A total of 10,110 participants completed the screening assessments. We excluded forty-six participants who had at least one missing value for the six threatening experiences items, resulting in a sample of 10,064 with full information on IOR experiences. Of this sample, 9935 participants provided information on their highest level of education. Due to the small sample size, those who identified themselves as neither female nor male were not further analyzed. The current analyses were based on a

Discussion

Our findings from a large community sample provided insights into the emergence of self-referential experiences in response to external events during a protracted period of social unrest and pandemic in Hong Kong. The findings suggested that external events can induce two levels of IOR experiences distinguishable using recipient specificity criteria: (1) feeling oneself as being referred to more than others (IOR-A), and (2) feeling oneself as being exclusively referred to (IOR-E). We found that

Conclusions

The current study afforded an opportunity to observe how IOR can be triggered by large-scale external stressful events, such as social unrest, which has not been examined in prior studies. We identified two levels of IOR with both similar and distinctive patterns of correlates, both of which were related to rumination associated with the unrest. In view of the possible risks that IOR can pose for the development of more severe psychopathological conditions, the relationship between IOR and

Twitter message

Can ideas of reference (IOR) be induced by social unrest and COVID-19? This large-scale timely study highlighted the interplay of intrinsic and extrinsic factors in triggering IOR of differing severity. Rumination may be a potential effective intervention target.

Declaration of competing interest

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article, all outside of the current submitted work: EYHC has received speaker honoraria from Otsuka and DSK BioPharma, research funding from Otsuka, participated in paid advisory boards for Janssen and DSK BioPharma, and received funding to attend conferences from Otsuka and DSK BioPharma. All other authors declare no competing interests.

Acknowledgements

We would like to express our utmost gratitude to all community members and professionals who have shared with us their thoughts and comments on the mental health survey and the individuals who have completed the survey.

Funding

The authors received no financial support for the research, authorship, and publication of this article.

Contributors

SWMY and EYHC designed the study, analyzed the data, interpreted results, and drafted the paper. All authors contributed to and approved the final manuscript.

Stephanie MY Wong. Ms. Stephanie Wong is currently undertaking doctoral research at the Department of Psychiatry of the University of Hong Kong (HKU). She obtained her degree in Bachelor of Social Sciences (double major in Psychology and Counselling) from HKU with first class honours in 2018. She has been working with the psychosis studies and intervention team of the Department of Psychiatry on various research topics involving clinical to community populations. Her research interests include

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    Stephanie MY Wong. Ms. Stephanie Wong is currently undertaking doctoral research at the Department of Psychiatry of the University of Hong Kong (HKU). She obtained her degree in Bachelor of Social Sciences (double major in Psychology and Counselling) from HKU with first class honours in 2018. She has been working with the psychosis studies and intervention team of the Department of Psychiatry on various research topics involving clinical to community populations. Her research interests include early intervention and prevention for at-risk populations, dimensional psychopathology, mental disorder and symptom prediction, and the development of novel technological approaches to mental health assessment and intervention.

    Christy LM Hui. Dr. Christy Hui is an Associate Professor at the Department of Psychiatry in the University of Hong Kong (HKU). She completed her Doctor of Philosophy (PhD) degree in 2009 and has been specializing in youth mental health, and psychosis studies with particular interest in relapse prevention, medication adherence, early intervention, and long-term outcomes of early psychosis. Her contribution has been recognized as one of the world's top 1% researchers by citations in HKU. She has published over 120 peer-reviewed articles and received the Young Scientist Award twice at international conferences, and the Outstanding Research Output Award locally.

    Corine SM Wong. Dr. Corine Wong is currently a Research Assistant Professor at the Department of Psychiatry, the University of Hong Kong (HKU). She completed her bachelor and master's degrees, as well as PhD at HKU. Prior to doctoral training, she was the Project Coordinator of the Hong Kong Mental Morbidity Survey, the first territory-wide psychiatric epidemiological study in Hong Kong. She is now the Chief Coordinator of the Hong Kong Youth Epidemiological Study of Mental Health (HK-YES), which aims to provide the first representative estimates of the prevalence, correlates and health economics for mental disorders among young people in Hong Kong.

    YN Suen. Dr. YN Suen is currently a Research Assistant Professor at the Department of Psychiatry, University of Hong Kong (HKU). She received nursing training in HKU and registered as a practicing nurse in 2009. She awarded her Doctor of Philosophy in field of Public Health in 2015. Her research interest revolves around the promotion of physical and mental well-being in the community and preventative mental health intervention for community women. The core of her research interests is to develop models of social processes in high-risk community samples to improve early detection of mental illness and optimize early interventions.

    Sherry KW Chan. Dr. Sherry Chan has completed the psychiatry specialist training both in United Kingdom and Hong Kong and obtained MPhil in Psychiatry at the University of Cambridge, and joined the Department of Psychiatry, the University of Hong Kong as Clinical Assistant Professor in 2009. Her research mainly focuses on the long-term outcomes of first-episode schizophrenia, mechanisms of treatment-resistant schizophrenia, and gaze perception of patients with schizophrenia. Dr. Chan has published over 110 peer-reviewed journal articles and three academic book chapters. More than 26 external research grants have been awarded with seven of them as the principal investigator.

    Edwin HM Lee. Dr. Edwin Lee is a Clinical Assistant Professor of the Department of Psychiatry, the University of Hong Kong. Dr Lee received the MRCPsych (UK) in 2006 and the FHKCPsych in 2010. He specializes in the field of psychosis with major interests in psychopharmacology and pharmacoepidemiology, exercise and cognitive interventions, neurocognitive science and neuroimaging and stigma and social psychiatry. He has published over 150 peer-reviewed articles and presented over 100 papers in international conferences.

    WC Chang. Dr. WC Chang is a Clinical Associate Professor at the Department of Psychiatry, the University of Hong Kong, a Principal Investigator of the State Key Laboratory of Brain & Cognitive Sciences. Dr. Chang received the MRCPsych (UK) in 2007, the FHKCPsych in 2009, and the FRCPsych (UK) and the MD in 2020. Dr. Chang's research interest includes early intervention and outcome of first-episode psychosis, clinical high-risk and psychosis prediction, negative symptoms and amotivation. He has published 133 articles in international peer-reviewed journals. He has received several research awards including the Clinical Research Fellowship by Hong Kong RGC and Young Investigator Award in two international organizations.

    Gloria HY Wong. Dr. Gloria Wong has started her research in delusions – specifically ideas of reference – since 2006. Her research focus on psychotic symptoms has led her to conduct transdiagnostic research, in populations with psychotic disorders, dementia, as well as at younger and older populations at-risk of developing mental disorders. Dr. Wong has training background in Philosophy, Psychology, and Psychiatry, and she is currently Assistant Professor at the Department of Social Work and Social Administration, The University of Hong Kong. Her work has led to over 80 publications, including co-editorship of a clinical guidebook summarizing early psychosis intervention development in Asia since 2001.

    Eric YH Chen. Professor Eric YH Chen is Chi-Li Pao Foundation Professor in Psychiatry and the Chair Professor and Head in the Department of Psychiatry at the University of Hong Kong (HKU). He has been leading the development of the early intervention for psychosis programme in Hong Kong since 2001 (the EASY programme of the Hospital Authority is one of the first and most comprehensive early psychosis programmes in Asia). Under his leadership, the Psychosis Studies and Intervention (PSI) team at HKU had published over 250 papers in leading international journals.

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