Review Article
Hypercoagulability of COVID-19 and Neurological Complications: A Review

https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.106163Get rights and content

Abstract

The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms. We will examine the landscape regarding this topic in this review in addition to current understandings of COVID-19 and hemostasis, treatment, and prevention, as well as vaccination.

Key Words

COVID-19
Anticoagulation
SARS-CoV-2
Neurologic outcomes

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Grant support: none

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