Accepted for/Published in: JMIR Cancer
Date Submitted: Nov 17, 2021
Date Accepted: Apr 10, 2022
Date Submitted to PubMed: Apr 18, 2022
CRDB: A CentralizedCancer Research DataBaseand an example use case mining correlation statistics of cancer and covid-19
ABSTRACT
Background:
The advancement of cancer research has been facilitated through freely available cancer literature, databases and tools. The age of genomics and big data has given rise to the need for cooperation and data sharing in order to make efficient use of this new information in the COVID-19 pandemic. Although there are many databases for cancer research their access is not easy due to different ways of processing and managing the data. There is absence of a unified platform to manage all of them in a transparent and more comprehensible way.
Objective:
In the herein research effort, an improved integrated cancer research database and platform is provided facilitating a deeper statistical insight of correlation between cancer and COVID-19 pandemic, unifying the collection of almost all previous published cancer databases and defining a model web database for cancer research,
Methods:
scoring databases on the basis of the variety types of cancer, sample size, completeness of omics results, and user interface. Databases examined and integrated include Data Portal database, Genomic database, Proteomic database, Expression database, Gene database and Mutation database. Moreover, the computational platform (PHP, HTML, CSS, and MySQL) is used to build CRDB for the cancer scientific community
Results:
To make it easy to search valuable information 85 cancer databases are provided in the form of table as well as the database of databases named Cancer research database (CRDB) has been built and herein presented. Furthermore, the CRDB has been herein equipped with unique navigation tools so that to be explored by three methods, i.e., any single database can be browsed by typing the name in the given search bar, while all Categories can be browsed by clicking on the name of the category, or image expression icon, a facility that could provide all the category databases on a single click. . In addition, based on the proposed platform, the status and diagnoses statistics of cancer during COVID-19 pandemic has been herein thoroughly investigated through using CRDB
Conclusions:
that this launch will sort, save, foster understanding and encourage the use of these resources in the cancer research environment which can be freely investigated and browsed by clicking at https://www.habdsk.org/crdb.php , and is planned to be updated timely. Thus, providing an easy to manage and understandable framework for mining knowledge for future researchers. Clinical Trial: NA
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.