Elsevier

Auris Nasus Larynx

Volume 49, Issue 1, February 2022, Pages 147-151
Auris Nasus Larynx

Patients with COVID-19-associated olfactory impairment also show impaired trigeminal function

https://doi.org/10.1016/j.anl.2021.07.012Get rights and content

Abstract

Objective

Next to olfactory function, the nose can also perceive chemestetic sensations mediated by the trigeminal nerve. While olfactory dysfunction as a symptom of COVID-19 is well described, there has been little research on the limitation of other nasal sensory inputs due to SARS-CoV-2 infection. The aim of this study was to determine possible limitations of nasal chemesthesis after COVID-19 infection by a psychophysiological diagnostic tool.

Methods

In 65 patients with a PCR-confirmed, former COVID-19 disease, olfaction was tested by means of a sniffin' sticks test, tasting by taste sprays and chemesthesis with a menthol dilution series. The subjective self-assessment of the patients was recorded via a questionnaire.

Results

We found a restriction of nasal chemesthesis and the extent correlated with the loss of smell, as well as with the values of the taste score, but not with subjective self-assessment.

Conclusion

Not only the ability to smell and taste, but also nasal chemesthesis is affected by COVID-19.

Keywords

SARS-CoV-2
Smell disorders
Trigeminal nerve
Chemesthesis
Sniffin’ Sticks

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