Mortality and case fatality rates of covid-19 in the state of goiás, brazil

Authors

  • Rodrigo Alexandre Trivilato aMaster of Public Health Program, School of Medicine, University of Limerick, V94 T9PX, Limerick, Ireland.
  • Tassiane Cristina Morais bEscola Superior de Ciências da Santa Casa de Misericórdia (EMESCAM), 29045-402 Vitória, ES, Brazil. cDepartamento de Educação Integrada em Saúde, Universidade Federal do Espírito Santo, 29075-910 Vitória, ES, Brazil.
  • Blanca Elena Guerrero Daboin Master of Public Health Program, School of Medicine, University of Limerick, V94 T9PX, Limerick, Ireland
  • Matheus Paiva Emidio Cavalcant aMaster of Public Health Program, School of Medicine, University of Limerick, V94 T9PX, Limerick, Ireland.
  • Lucas Cauê Jacintho d Divisão de Imunologia e Alergia Clínica, Departamento de Medicina, Faculdade de Medicina da Universidade de São Paulo, 05403-000 São Paulo, SP, Brazil.
  • Rodrigo Daminello Raimundo eLaboratório de Delineamento de Estudos e Escrita Científica, Centro Universitário FMABC, 09060-870 Santo André, SP, Brazil.
  • Jorge de Oliveira Eichemberg eLaboratório de Delineamento de Estudos e Escrita Científica, Centro Universitário FMABC, 09060-870 Santo André, SP, Brazil.
  • Khalifa Elmusharaf aMaster of Public Health Program, School of Medicine, University of Limerick, V94 T9PX, Limerick, Ireland.
  • Carlos Eduardo Siqueira aMaster of Public Health Program, School of Medicine, University of Limerick, V94 T9PX, Limerick, Ireland.: fDepartment of Urban Planning and Community Development, School for the Environment, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125.
  • José Luiz de Figueiredo gDepartamento de Cirurgia - Universidade Federal de Pernambuco, Brazil.

DOI:

https://doi.org/10.36311/jhgd.v31.12781

Keywords:

case fatality rate, COVID-19, epidemiology, mortality, trends

Abstract

Introduction: the initial spread of the pandemic in Brazil was mainly affected by patterns of socioeconomic vulnerability. It should be noted that the Central-West region of Brazil is one of the regions with the lowest number of cases, but the states of this region together have the highest mortality rate of COVID-19 in the country. Goiás was the most affected state of this region, with the highest number of deaths in the area.

Objective: to assess the incidence of mortality and lethality caused by COVID-19 from March 2020 to June 2021 in the State of Goiás, Brazil.

Methods: an ecological study, using a series of time series of public and official data of the Department of Health of the State of Goiás, Brazil. Information was collected on cases and deaths from COVID-19 from March 2020 to June 2021. Mortality, case fatality, and incidence rates were calculated. The Prais-Wisten regression model was used to build time series. The daily percent change (DPC) and the effective reproductive number (Rt) were estimated.

Results: Goiás had a predominance of a greater viral spread during the first and the beginning of the second wave, with Rt higher than 1. The second wave from December 2020 to June 2021 was more lethal and had higher mortality rates than the first wave. It was observed, higher scores of case fatality and mortality belonged to males and the elderly.

Conclusion: an analysis of mortality and case fatality rates helps understand the COVID-19 pandemic behavior in Goiás. It is essential to monitor epidemiological indicators and strengthen intervention strategies to contain the pandemic in this state.

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References

Wang C, Xiao X, Feng H, Hong Z, Li M, Tu N, Li X, Wang K, Bu L. Ongoing COVID-19 Pandemic: A Concise but Updated Comprehensive Review. Curr Microbiol. 2021;78(5):1718-1729. DOI: 10.1007/s00284-021-02413-z.

Johns Hopkins University. Center for systems science and engineering (csse). Covid-19 dashboard. [Internet]. [cited 2021 jul. 5]. Available from: https://coronavirus.jhu.edu/map.html.

Castro MC, Kim S, Barberia L, Ribeiro AF, Gurzenda S, Ribeiro KB, Abbott E, Blossom J, Rache B, Singer BH. Spatiotemporal pattern of COVID-19 spread in Brazil. Science. 2021;372(6544):821-826. DOI: 10.1126/science.abh1558.

Massuda A, Hone T, Leles FAG, de Castro MC, Atun R. The Brazilian health system at crossroads: progress, crisis and resilience. BMJ Glob Health. 2018;3(4):e000829. DOI: 10.1136/bmjgh-2018-000829.

Rocha R, Atun R, Massuda A, Rache B, Spinola P, Nunes L, Lago M, Castro MC. Effect of socioeconomic inequalities and vulnerabilities on health-system preparedness and response to COVID-19 in Brazil: a comprehensive analysis. Lancet Glob Health. 2021;9(6):e782-e792. DOI: 10.1016/S2214-109X(21)00081-4..

Abreu LC de. The path of humanity in the pandemic of COVID-19: the choice of the realistic, optimist or pessimist scenario. J Hum Growth Dev. 2021; 31(1):05-08. DOI: http://dx.doi.org/10.36311/jhgd.

Coronavirus Brasil, Painel Geral [Internet]. [cited 2021 jul. 10]. Available from: https://covid.saude.gov.br/.

Instituto Brasileiro de Geografia e Estatística. Cidades e Estados. [Internet]. [cited 2021 jul. 10]. Available from: https://www.ibge.gov.br/cidades-e-estados.

Secretaria de Estado de Gestão e Planejamento, Goiás. Goiás em Dados 2017 [Internet]. [cited 2021 jul. 10]. Avaliable from: https://www.imb.go.gov.br/files/docs/publicacoes/Goiás-em-dados/godados2017.pdf.

COVID-19. Secretaria de Estado de Saúde de Goiás [Internet]. [cited 2021 jul. 17]. Available from: https://indicadores.saude.go.gov.br/pentaho/api/repos/:coronavirus:paineis:painel.wcdf/generatedContent

Abreu LC, Elmusharaf K, Siqueira CEG. A time-series ecological study protocol to analyze trends of incidence, mortality, lethality of COVID-19 in Brazil. J Hum Growth Dev. 2021; 31(3):491-495. DOI: 10.36311/jhgd.v31.12667

International Statistical Classification of Diseases and Related Health Problems 10th Revision. World Health Organization [internet]. 2020 [cited: 2021 June 20]. Available from: https://icd.who.int/browse10/2019/en#/U04.

Cori A, Ferguson NM, Fraser C, Cauchemez S. A new framework and software to estimate time-varying reproduction numbers during epidemics. Am J Epidemiol. 2013;178(9):1505-1512. DOI: 10.1093/aje/kwt133.

Thompson RN, Stockwin JE, van Gaalen RD, Polonsky JA, Kamvar ZN, Demarsh PA, Dahlqwist E, Li S, Miguel E, Jombart T, Lessler J, Cauchemez S, Cori A. Improved inference of time-varying reproduction numbers during infectious disease outbreaks. Epidemics. 2019;29:100356. DOI: 10.1016/j.epidem.2019.100356.

Ali ST, Yeung A, Shan S, Wang L, Gao H, Du Z, Xu XK, Wu P, Lau EHY, Cowling BJ. Serial intervals and case isolation delays for COVID-19: a systematic review and meta-analysis. Clin Infect Dis.2021:ciab491. DOI: 10.1093/cid/ciab491.

Prete CA, Buss L, Dighe A, Porto VB, da Silva Candido D, Ghilardi F, Pybus OG, de Oliveira WK, Croda JHR, Sabino EC, Faria NR, Donnelly CA, Nascimento VH. Serial interval distribution of SARS-CoV-2 infection in Brazil. J Travel Med. 2021;28(2):taaa115. DOI: 10.1093/jtm/taaa115.

Datasus. Informações de Saúde - TABNET. Demográficas e Socioeconômica. População residente [Internet]. [cited 2021 jul. 20]. Available from: http://www2.datasus.gov.br/DATASUS/index.php?area=0206&id=6942.

Antunes JLF, Cardoso MRA. Uso da análise de séries temporais em estudos epidemiológicos. Epidemiol Serv Saúde 2015;24(3):565-576. DOI:10.5123/S1679-49742015000300024.

Sistema IBGE de Recuperação Automática. Banco de Tabelas estatística [Internet]. [cited 2021 jul. 15]. Available from: https://sidra.ibge.gov.br/home/ipp/brasil.

CNESNet. Cadastro Nacional de Estabelecimentos de Saúde [Internet]. [cited 2021 jul. 15]. Available from: http://cnes.datasus.gov.br/.

Governo de Goiás. Governo quer atingir 55% de isolamento com quarentena intermitente – 2020 [Internet]. [cited 2021 jul. 07]. Available from: https://www.Goiás.gov.br/index.php/servico/96-coronavirus/122171-caiado-quer-atingir-55-de-isolamento-com-quarentena-intermitente.

Fundação Oswaldo Cruz. Observatório covid-19. Boletim extraordinário, 6 de abril de 2021 [Internet]. [cited 2021 jul. 09]. Available from: https://www.arca.fiocruz.br/bitstream/icict/46591/2/boletim_extraordinario_2021-abril-06-red_2.pdf.

Secretaria de Saúde do Estado de Goiás. Nota informativa – identificação de novas variantes do coronavírus em municípios goianos [Internet]. [cited 2021 jul. 09]. Available from: https://www.saude.go.gov.br/coronavirus/noticias-coronavirus/12618-nota-informativa-identificacao-de-novas-variantes-do-coronavirus-em-municipios-goianos.

Governo de Goiás. Pesquisa financiada pela Fapeg identifica variante delta do coronavírus, em Goiânia [Internet]. [cited 2021 jul. 09]. Avaliable: https://www.Goiás.gov.br/servico/30-ciencia-e-tecnologia/125243-pesquisa-financiada-pela-fapeg-identifica-variante-delta-do-em-goi%c3%a2nia.html.

Almubaid Z, Al-Mubaid H. Analysis and comparison of genetic variants and mutations of the novel coronavirus SARS-CoV-2. Gene Rep. 2021;23:101064. DOI: 10.1016/j.genrep.2021.101064.

OPAS. (2021) ‘Epidemiological update: occurrence of variants of sars-cov-2 in the americas - 20 january 2021 [Internet]. [cited 2021 jul.10]. Avaliable from: https://iris.paho.org/bitstream/handle/10665.2/53234/epiupdate26january2021_por.pdf?sequence=1&isallowed=y.

Callaway E. Delta coronavirus variant: scientists brace for impact, Nature, 595(7865):17-18. DOI: 10.1038/d41586-021-01696-3.

Hoffmann M, Arora P, Groß R, Seidel A, Hörnich BF, Hahn AS, Krüger N, Graichen L, Hofmann-Winkler H, Kempf A, Winkler MS, Schulz S, Jäck HM, Jahrsdörfer B, Schrezenmeier H, Müller M, Kleger A, Münch J, Pöhlmann S. SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies. Cell. 2021;184(9):2384-2393.e12. DOI: 10.1016/j.cell.2021.03.036.

Secretaria de Saúde do Estado de Goiás. Atualização sobre a covid-19 em Goiás e doses da vacina já aplicadas - 10/06/2021 [Internet]. [cited 2021 jul. 07]. Avaliable from: https://www.saude.go.gov.br/coronavirus/noticias-coronavirus/13088-atualizacao-sobre-a-covid-19-em-Goiás-e-doses-da-vacina-ja-aplicadas-10-06-2021.

Pimentel RMM, Daboin BEG, Oliveira AG, Macedo JrH . The dissemination of COVID-19: an expectant and preventive role in global health. J Hum Growth Dev. 2021;30(1):135-140. DOI http://doi.org/10.7322/jhgd.v30.9976.

Castro MC, Gurzenda S, Turra CM, Kim S, Andrasfay T, Goldman N. Reduction in life expectancy in Brazil after COVID-19. Nat Med. 2021;27(9):1629-1635. DOI: 10.1038/s41591-021-01437-z. z.

Dourado P, Santos Filho A, Vieira L, Lima A. Covid-19 vulnerabilidade e letalidade. Subsecretaria de saúde gerência de informações estratégicas em saúde conecta-sus. P.1-9 [Internet]. [cited 2021 jul. 10]. Avaliable from: https://www.saude.go.gov.br/files//conecta-sus/produtos-tecnicos/i%20-%202021/covid-19%20-%20vulnerabilidade,%20gravidade%20e%20letalidade.pdf.

De Souza FSH, Hojo-Souza NS, Batista BDO, da Silva CM, Guidoni DL. On the analysis of mortality risk factors for hospitalized COVID-19 patients: A data-driven study using the major Brazilian database. PLoS One. 2021;16(3):e0248580. DOI: 10.1371/journal.pone.0248580.

Secretaria de Saúde do Estado de Goiás. Governo de Goiás começa a vacinar contra covid-19 idosos de 70 anos com 129 mil doses recebidas, número recorde para primeira aplicação [Internet]. [cited 2021 jul. 10]. Avaliable from: https://www.saude.go.gov.br/noticias/12628-governo-de-Goiás-comeca-a-vacinar-contra-covid-19-idosos-de-70-anos-com-129-mil-oses-recebidas-numero-recorde-para-primeira-aplicacao.

Governo de Goiás. Vacinação de idosos deve terminar em abril, afirma caiado [Internet]. [cited 2021 jul. 10]. Avaliable from: https://www.Goiás.gov.br/servico/97-pandemia/124684-vacina%c3%a7%c3%a3o-de-idosos-deve-terminar-em-abril,-afirma-caiado.html. [accessed: 10 de July de 2021].

Green MS, Nitzan D, Schwartz N, Niv Y, Peer V. Sex differences in the case-fatality rates for COVID-19-A comparison of the age-related differences and consistency over seven countries. PLoS One. 2021;16(4):e0250523. DOI: 10.1371/journal.pone.0250523.

Peckham H, de Gruijter NM, Raine C, Radziszewska A, Ciurtin C, Wedderburn LR, Rosser EC, Webb K, Deakin CT. Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission. Nat Commun. 2020;11(1):6317. DOI: 10.1038/s41467-020-19741-6.

Published

2021-12-01

Issue

Section

ORIGINAL ARTICLES