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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jun 3, 2020
Date Accepted: Jan 18, 2021
Date Submitted to PubMed: Feb 8, 2021

The final, peer-reviewed published version of this preprint can be found here:

Precision Assessment of COVID-19 Phenotypes Using Large-Scale Clinic Visit Audio Recordings: Harnessing the Power of Patient Voice

Barr PJ, Ryan J, Jacobson NC

Precision Assessment of COVID-19 Phenotypes Using Large-Scale Clinic Visit Audio Recordings: Harnessing the Power of Patient Voice

J Med Internet Res 2021;23(2):e20545

DOI: 10.2196/20545

PMID: 33556031

PMCID: 7899201

Precision Assessment of COVID-19 Phenotypes Using Large-Scale Clinic Visit Audio Recordings: Harnessing the Power of the Patient Voice

  • Paul J Barr; 
  • James Ryan; 
  • Nicholas C Jacobson

ABSTRACT

The novel coronavirus (SARS-CoV-2) and its related disease, COVID-19, are exponentially increasing across the world, yet there is still uncertainty about the clinical phenotype. Natural Language Processing (NLP) and machine learning may hold one key to quickly identify individuals at high risk for COVID-19 and understand key symptoms in its clinical manifestation and presentation. In healthcare, such data often come the medical record, yet when overburdened, clinicians may focus on documenting widely reported symptoms that appear to confirm the diagnosis of COVID-19, at the expense of infrequently reported symptoms. A comprehensive record of the clinic visit is required—an audio recording may be the answer. If done at scale, a combination of data from the EHR and recordings of clinic visits can be used to power NLP and machine learning models, quickly creating a clinical phenotype of COVID-19. We propose the creation of a pipeline from the audio/video recording of clinic visits to the clinical symptomatology model and prediction of COVID-19 infection. With vast amounts of data available, we believe a prediction model can be quickly developed that could promote the accurate screening of individuals at risk of COVID-19 and identify patient characteristics predicting a greater risk of a more severe infection. If clinical encounters are recorded and our NLP is adequately refined, then benchtop-virology will be better informed and risk of spread reduced. While recordings of clinic visits are not the panacea to this pandemic, they are a low cost option with many potential benefits that have only just begun to be explored.


 Citation

Please cite as:

Barr PJ, Ryan J, Jacobson NC

Precision Assessment of COVID-19 Phenotypes Using Large-Scale Clinic Visit Audio Recordings: Harnessing the Power of Patient Voice

J Med Internet Res 2021;23(2):e20545

DOI: 10.2196/20545

PMID: 33556031

PMCID: 7899201

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© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.

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