Componentes alimenticios, estado de ánimo y su relación con el sistema inmune en COVID-19

Autores/as

DOI:

https://doi.org/10.29105/respyn20.4-7

Palabras clave:

Covid-19, compuestos bioactivos, estado de ánimo, sistema inmune

Resumen

Introducción: El SARS-CoV-2 causante del Covid-19 no solo afecta al sistema inmunológico, sino también el confinamiento tiene un gran impacto sobre la salud mental y fisiológica de la población. Objetivo: Describir los compuestos alimenticios que mejoran el estado de ánimo y su influencia en el fortalecimiento del sistema inmune, durante la pandemia por Covid-19. Metodología: Se consultaron las bases de datos como Google académico y PubMed (MEDLINE), y se incluyeron artículos originales y de revisión. Resultados: Los compuestos bioactivos presentes en los alimentos como probióticos, triptófano, L-Teanina y Vitamina D, mejoran el estado de ánimo como ansiedad, estrés y depresión, a su vez los probióticos, antioxidantes como la vitamina C, triptófano y vitaminas liposolubles (A, D y E) muestran un impacto positivo en el sistema inmunológico. Limitaciones: La diversidad de estados de ánimo aumenta el sesgo en los resultados por el empleo de diferentes herramientas metodológicas. Conclusiones: En tiempos de pandemia es importante mantener un estado de ánimo y un sistema inmunológico óptimo, concluyendo que el consumo de componentes bioactivos como probióticos, triptófano, L-Teanina y Vitaminas A D C y E a través de la dieta puede ayudar a mejorar el estado de ánimo y al fortalecimiento del sistema inmunológico.

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Biografía del autor/a

Leticia Interián-Gómez, Universidad de Guadalajara

Departamento de Biología Molecular y Genómica

Karina Gonzalez-Becerra, Universidad de Guadalajara

Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara.

Citas

Anglin, R., Samaan, Z., Walter, S., & McDonald, S. (2013). Vitamin D deficiency and depression in adults: Systematic review and meta-analysis. Br J Psychiatry, 202(2), 100-107. doi:10.1192/bjp.bp.111.106666 DOI: https://doi.org/10.1192/bjp.bp.111.106666

Akkasheh, G., Kashani-Poor, Z., Tajabadi-Ebrahimi, M., Jafari, P., Akbari, H., et al. (2016). Clinical and metabolic response to probiotic administration in patients with major depressive disorder. Nutrition. 32(3), 315-320. doi: 10.1016/j.nut.2015.09.003 DOI: https://doi.org/10.1016/j.nut.2015.09.003

Asmundson, G. J., Paluszek, M. M., Landry, C. A., Rachor, G. S., McKay, D., & Taylor, S. (2020). Do pre-existing anxiety-related and mood disorders differentially impact COVID-19 stress responses and coping?. J Anxiety Disord. 74, 102271. doi.org/10.1016/j.jiph.2020.06.021 DOI: https://doi.org/10.1016/j.janxdis.2020.102271

Berggren, A., Lazou-Ahrén, I., Larsson, N., Önning, G. (2011). Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections. Eur J Nutr, 50(3), 203-10. doi: 10.1007/s00394-010-0127-6 DOI: https://doi.org/10.1007/s00394-010-0127-6

Bizzaro, G., Antico, A., Fortunato, A., & Bizzaro, N. (2017). Vitamin D and Autoimmune Diseases: Is Vitamin D Receptor (VDR) Polymorphism the Culprit?. Isr Med Assoc J : IMAJ, 19(7), 438–443. PMID: 28786260

Bravo, R., Matito, S., Cubero, J., Paredes, S. D., Franco, L., Rivero, M., Rodríguez, A. B., & Barriga, C. (2013). Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans. Age (Dordrecht, Netherlands), 35(4), 1277–1285. doi.org/10.1007/s11357-012-9419-5 DOI: https://doi.org/10.1007/s11357-012-9419-5

Butlera, M. J., & Barrientos, R. M. (2020). The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun, 87, 53–54. doi.org/10.1016/j.bbi.2020.04.040 DOI: https://doi.org/10.1016/j.bbi.2020.04.040

Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. doi.org/10.3390/nu9111211 DOI: https://doi.org/10.3390/nu9111211

Debelo, H., Novotny, J. A., & Ferruzzi, M. G. (2017). Vitamin A. Advances in Nutrition: An International Review Journal, 8(6), 992-994. doi.org/10.3945/an.116.014720 DOI: https://doi.org/10.3945/an.116.014720

Díaz-Castrillón, F. J., & Toro-Montoya, A. I. (2020). SARS-CoV-2/COVID-19: el virus, la enfermedad y la pandemia. Med Lab, 24(3), 183-205. doi.org/10.36384/01232576.268 DOI: https://doi.org/10.36384/01232576.268

Dragoş, D. y Tănăsescu, M. D. (2010). The effect of stress on the defense systems. J Med Life. 3(1), 10-18. PMID: 20302192

Đogaš, Z., Kalcina, L. L., Dodig, I. P., Demirović, S., Madirazza, K., Valić, M., & Pecotić, R. (2020). The effect of COVID-19 lockdown on lifestyle and mood in Croatian general population: a cross-sectional study. Croat Med J. 61(4), 309. doi: 10.3325 / cmj.2020.61.309 DOI: https://doi.org/10.3325/cmj.2020.61.309

Dubey, S., Biswas, P. Ghosh, R. Chattarjee, S. Dubey, M. J., Chatterjee, S., Lahiri, D., Lavie, C. J. (2020). Psychosocial impact of COVID-19. Diabetes Metab Syndr, 14(5), 779-788. doi:10.1016/j.dsx.2020.05.035 DOI: https://doi.org/10.1016/j.dsx.2020.05.035

Gao, J., Xu, K., Liu, H., Liu, G., Bai, M., Peng, C., Li, T., Yin, Y. (2018). Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism. Front Cell Infect Microbiol, 6,8-13. doi: 10.3389/fcimb.2018.00013 DOI: https://doi.org/10.3389/fcimb.2018.00013

Goncalves-Mendes, N., Talvas, J., Dualé, C., Guttmann, A., Corbin, V., et al. (2019). Impact of Vitamin D Supplementation on Influenza Vaccine Response and Immune Functions in Deficient Elderly Persons: A Randomized Placebo-Controlled Trial. Front Immunol, 10; 65. doi.org/10.3389/fimmu.2019.00065 DOI: https://doi.org/10.3389/fimmu.2019.00065

Haskell-Ramsay, C. F., Stuart, R. C., Okello, E. J., & Watson, A. W. (2017). Cognitive and mood improvements following acute supplementation with purple grape juice in healthy young adults. Eur J Nutr, 56(8), 2621–2631. doi.org/10.1007/s00394-017-1454-7 DOI: https://doi.org/10.1007/s00394-017-1454-7

Hemila, H. (2016). Vitamin E administration may decrease the incidence of pneumonia in elderly males. Clinical Interventions in Aging, Volume 11, 1379–1385. doi.org/10.2147/cia.s114515 DOI: https://doi.org/10.2147/CIA.S114515

Hornsby, E., Pfeffer, P. E., Laranjo, N., Cruikshank, W., Tuzova, M., Litonjua, A. A., Weiss, S. T., Carey, V. J., O’Connor, G., & Hawrylowicz, C. (2018). Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial. J Allergy Clin Immunol, 141(1), 269-278.e1. doi.org/10.1016/j.jaci.2017.02.039 DOI: https://doi.org/10.1016/j.jaci.2017.02.039

Infusino, F., Marazzato, M., Mancone, M., Fedele, F., Mastroianni, et al. (2020). Diet Supplementation, Probiotics, and Nutraceuticals in SARS-CoV-2 Infection: A Scoping Review Nutrients. 12(6), 1718. doi.org/10.3390/nu12061718 DOI: https://doi.org/10.3390/nu12061718

Ingram, J., Maciejewski, G., & Hand, C. J. (2020). Changes in diet, sleep, and physical activity are associated with differences in negative mood during COVID-19 lockdown. Front Psychol. 11, 2328. doi.org/10.3389/fpsyg.2020.588604 DOI: https://doi.org/10.3389/fpsyg.2020.605118

Jaatinen, N., Korpela, R., Poussa, T., Turpeinen, A., Mustonen, S., Merilahti, J., Peuhkuri, K., (2014). Effects of daily intake of yoghurt enriched with bioactive components on chronic stress responses: a double-blinded randomized controlled trial. Int J Food Sci Nutr, 65(4), 507–514. doi: 10.3109/09637486.2014.880669 DOI: https://doi.org/10.3109/09637486.2014.880669

Jenkins, T. A., Nguyen, J. C., Polglaze, K. E., & Bertrand, P. P. (2016). Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients, 8(1); 56. doi.org/10.3390/nu8010056 DOI: https://doi.org/10.3390/nu8010056

Khadangi, F., & Azzi, A. (2019). Vitamin E - The Next 100 Years. IUBMB life, 71(4), 411–415. doi.org/10.1002/iub.1990 DOI: https://doi.org/10.1002/iub.1990

Khalid, S., Barfoot, K. L., May, G., Lamport, D. J., Reynolds, S. A., & Williams, C. M. (2017). Effects of Acute Blueberry Flavonoids on Mood in Children and Young Adults. Nutrients, 9(2), 158. doi.org/10.3390/nu9020158 DOI: https://doi.org/10.3390/nu9020158

Kozłowska, A., Szostak-Wegierek, D. (2014). Flavonoids food sources and health benefits. Rocz Panstw Zakl Hig, 65(2), 79-85.

Kurihara, S., Hiraoka, T., Akutsu, M., Sukegawa, E., Bannai, M., & Shibahara, S. (2010). Effects of (L)-cystine and (L)-theanine supplementation on the common cold: a randomized, double-blind, and placebo-controlled trial. J Amino Acids, 2010, 307475. DOI: 10.4061/2010/307475 DOI: https://doi.org/10.4061/2010/307475

Lewis, E. D., Meydani, S. N., & Wu, D. (2018). Regulatory role of vitamin E in the immune system and inflammation. IUBMB Life, 71(4), 487-494. doi.org/10.1002/iub.1976 DOI: https://doi.org/10.1002/iub.1976

Lindseth, G., Helland, B. y Caspers, J., (2015). The Effects of Dietary Tryptophan on Affective Disorders. Arch Psychiatr Nurs, 29(2), 102-7. doi:10.1016/j.apnu.2014.11.008 DOI: https://doi.org/10.1016/j.apnu.2014.11.008

Marsland, B.J. (2016). Regula la inflamación con metabolitos microbianos . Nat Medicina. 22 , 581–583. 10.1038 / nm.4117 DOI: https://doi.org/10.1038/nm.4117

Marsh, W. K., Penny, J. L., & Rothschild, A. J. (2017). Vitamin D supplementation in bipolar depression: A double blind placebo controlled trial. J Psychiatr Res, 95, 48–53. doi.org/10.1016/j.jpsychires.2017.07.021 DOI: https://doi.org/10.1016/j.jpsychires.2017.07.021

Medlineplus. (2020). El estrés y su salud. https://medlineplus.gov/spanish/ency/article/003211.htm#:~:text=El%20estr%C3%A9s%20es%20un%20sentimiento,a%20un%20desaf%C3%ADo%20o%20demanda.

Naranjo-Pereira, M. L. (2009). Una revisión teórica sobre el estrés y algunos aspectos relevantes de éste en el ámbito educativo. Rev Educación: 33 (2), 171-190. DOI 10.15517/REVEDU.V33I2.511 DOI: https://doi.org/10.15517/revedu.v33i2.511

Pérez-Fuentes, M. D. C., Molero Jurado, M. D. M., Martos Martínez, Á., & Gázquez Linares, J. J. (2020). Threat of COVID-19 and emotional state during quarantine: Positive and negative affect as mediators in a cross-sectional study of the Spanish population. PloS one, 15(6). doi.org/10.1371/journal.pone.0235305 DOI: https://doi.org/10.1371/journal.pone.0235305

Pincikova, T., Paquin-Proulx, D., Sandberg, J. K., Flodström-Tullberg, M., & Hjelte, L. (2017). Vitamin D treatment modulates immune activation in cystic fibrosis. Clinical & Experimental Immunology, 189(3), 359–371. doi.org/10.1111/cei.12984 DOI: https://doi.org/10.1111/cei.12984

Sakamoto, F., Pereira, R., Bueno, A., Santos, H. (2019). Psychotropic effects of L-theanine and its clinical properties: From the management of anxiety and stress to a potential use in schizophrenia. Pharmacol Res, 147. doi.org/10.1016/j.phrs.2019.104395 DOI: https://doi.org/10.1016/j.phrs.2019.104395

Shakoor, H., Feehan, J., Al Dhaheri, A. S., Ali, H. I., Platat, C., Ismail, L. C., Stojanovska, L. (2021). Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas, 143, 1-9. doi.org/10.1016/j.maturitas.2020.08.003 DOI: https://doi.org/10.1016/j.maturitas.2020.08.003

Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS. (2015). A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain Behav Immun, 48; 258-64. doi.org/10.1016/j.bbi.2015.04.003 DOI: https://doi.org/10.1016/j.bbi.2015.04.003

Speth, M. M., Singer‐Cornelius, T., Oberle, M., Gengler, I., Brockmeier, S. J., & Sedaghat, A. R. (2020). Mood, anxiety and olfactory dysfunction in COVID‐19: evidence of central nervous system involvement?. The Laryngoscope. doi.org/10.1002/lary.28964 DOI: https://doi.org/10.1002/lary.28964

Szodoray P, Horvath IF, Papp G, Barath S, Gyimesi E, Csathy L, Kappelmayer J, Sipka S, Duttaroy AK, Nakken B, Zeher M (2010). The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome. Rheumatology (Oxford). 49(2); 211-7. doi: 10.1093/rheumatology/kep374 DOI: https://doi.org/10.1093/rheumatology/kep374

Van-Rheenen, T. E., Meyer, D., Neill, E., Phillipou, A., Tan, E. J., et al. (2020). Mental health status of individuals with a mood-disorder during the COVID-19 pandemic in Australia: Initial results from the COLLATE project. Pharmacol Res. 275; 69–77. doi.org/10.1016/j.jad.2020.06.037 DOI: https://doi.org/10.1016/j.jad.2020.06.037

Wang, C., Pan, R., Wan, X., Tan, Y., Xu, L., et al. (2020). Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China. Int J Environ Res Public Health, 17(5), 1729. Doi: 10.3390 / ijerph17051729 DOI: https://doi.org/10.3390/ijerph17051729

Waqas Khan, H. M., Parikh, N., Megala, S. M., & Predeteanu, G. S. (2020). Unusual Early Recovery of a Critical COVID-19 Patient After Administration of Intravenous Vitamin C. Am J Case Rep, 21. doi.org/10.12659/ajcr.925521 DOI: https://doi.org/10.12659/AJCR.925521

White, D. J., de Klerk, S., Woods, W., Gondalia, S., Noonan, C., & Scholey, A. B. (2016). Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients, 8(1), 53. doi.org/10.3390/nu8010053 DOI: https://doi.org/10.3390/nu8010053

Xu D. P., Li Y., Meng X., Zhou T., Zhou Y., et al. (2017). Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources. Int J Mol Sci, 18(1), 96. doi: 10.3390/ijms18010096 DOI: https://doi.org/10.3390/ijms18010096

Yan, F. y Polk, DB (2011). Probiotics and immune health. Opinión actual en gastroenterología, 27(6), 496–501. doi.org/10.1097/MOG.0b013e32834baa4d DOI: https://doi.org/10.1097/MOG.0b013e32834baa4d

Yoto, A., Motoki, M., Murao, S., Yokogoshi. (2012). Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J Physiol Anthropol, 31(1), 1-9. doi: 10.1186/1880-6805-31-28 DOI: https://doi.org/10.1186/1880-6805-31-28

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2021-09-30

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Interián-Gómez, L., Aguila-Gutiérrez, S. E., Esquivias-López, K. M., Pulido-De la Cruz, V. A., Silva-Arzola, N. J., & Gonzalez-Becerra, K. (2021). Componentes alimenticios, estado de ánimo y su relación con el sistema inmune en COVID-19. RESPYN Revista Salud Pública Y Nutrición, 20(4), 73–86. https://doi.org/10.29105/respyn20.4-7

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