COVID-19 detection in chest X-ray images using deep boosted hybrid learning

https://doi.org/10.1016/j.compbiomed.2021.104816Get rights and content

Highlights

  • Two new frameworks, named as DHL and DBHL are proposed for COVID-19 detection in chest X-ray images.

  • DHL framework exploits the learning capacity of the developed COVID-RENets and SVM. COVID-RENet systematically learns the region homogeneity and boundaries features.

  • In the DBHL framework, rich information boosted representation is obtained by concatenating the feature space of the COVID-RENets.

  • The proposed frameworks significantly decrease false negatives as compared to existing deep CNNs.

  • A web predictor is developed for assisting the radiologist in making accurate COVID-19 decisions.

Abstract

The new emerging COVID-19, declared a pandemic disease, has affected millions of human lives and caused a massive burden on healthcare centers. Therefore, a quick, accurate, and low-cost computer-based tool is required to timely detect and treat COVID-19 patients. In this work, two new deep learning frameworks: Deep Hybrid Learning (DHL) and Deep Boosted Hybrid Learning (DBHL), is proposed for effective COVID-19 detection in X-ray dataset. In the proposed DHL framework, the representation learning ability of the two developed COVID-RENet-1 & 2 models is exploited individually through a machine learning (ML) classifier. In COVID-RENet models, Region and Edge-based operations are carefully applied to learn region homogeneity and extract boundaries features. While in the case of the proposed DBHL framework, COVID-RENet-1 & 2 are fine-tuned using transfer learning on the chest X-rays. Furthermore, deep feature spaces are generated from the penultimate layers of the two models and then concatenated to get a single enriched boosted feature space. A conventional ML classifier exploits the enriched feature space to achieve better COVID-19 detection performance. The proposed COVID-19 detection frameworks are evaluated on radiologist's authenticated chest X-ray data, and their performance is compared with the well-established CNNs. It is observed through experiments that the proposed DBHL framework, which merges the two-deep CNN feature spaces, yields good performance (accuracy: 98.53%, sensitivity: 0.99, F-score: 0.98, and precision: 0.98). Furthermore, a web-based interface is developed, which takes only 5–10s to detect COVID-19 in each unseen chest X-ray image. This web-predictor is expected to help early diagnosis, save precious lives, and thus positively impact society.

Keywords

COVID-19
X-ray
Transfer learning
Hybrid learning
Convolutional neural network
Deep learning and SVM

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