AUCTORES
Globalize your Research
Case Report | DOI: https://doi.org/10.31579/2768-0487/061
*Corresponding Author: Dan Jiang, Hallam Institute of TCM, 439 Glossop Road Sheffield S10 2PR UK.
Citation: D Jiang. (2022). Diagnosis and Management of Infected or Suspected Patients with Covid-19 A study of 48 Cases in the UK. Journal of Clinical and Laboratory Research. 5(1); DOI:10.31579/2768-0487/061
Copyright: ©2022 Dan Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 09 November 2021 | Accepted: 30 November 2021 | Published: 04 January 2022
Keywords: covid-19; corona virus; chinese herbal medicine; TCM
Covid-19 is a pandemic infective disease, which has been erupting throughout the whole world from 2020 to 2021. There have been at the time of reviewing more than a hundred million cases (102,399,513) of infection, and more than 2 million deaths (2,217,005) in more than 200 countries; this information is taken from the Covid-19 daily situation report issued on 1st Feb 2021 by WHO. The pandemic was also declared as an outbreak of Public Health Emergency of International Concern on 30th Jan 2020 by WHO. No effective treatment model has yet been confirmed by conventional western medicine, but some herbal treatments used in China can be recognized as having positive results in Covid-19 cases. This pandemic disaster has been severely damaging to quality of life, disturbing social communication, economic development and the progress of humanity.
Successful results were first reported from temporary hospitals (Fangcang Hospitals set up in arenas and exhibition spaces) in Wuhan, China, where more than 90% of patients treated with Chinese herbal medicine were prevented by transferring from the minor or milder stages of the disease to the severe or critical stage. In all of them the positive PCR became negative; herbs were involved in the rescue and treatment of severe and critical cases in ICU’s in hospitals as well. It was an important factor in how Covid-19 was controlled so quickly in China.
The author recruited both confirmed and suspected Covid-19 patients through social media (WeChat, WhatsApp, Internet, message etc.) as a volunteer TCM consultant from March 2020, during the first Lockdown phase in UK. It was quickly realized that the appearance of the tongue provides special and significant information for identifying whether Covid-19 is present and shows its severity, from a TCM perspective, as the degree and type of dampness accumulated within the body. Herbal prescriptions were sent by post for patients’ treatment according to their clinical findings, virus exposure history and tongue information (from photos). Similar positive effects were found as in China, and treatment reports and results are summarized here. The author believes there are many herbal medicines that can be effective in controlling the Sars-Cov-2 virus, and that prescribing the appropriate formula to match each individual case is the key point for TCM control of Covid-19. Chinese herbal medicine is the most effective current treatment method that can prevent cases in the minor and ordinary stages from progressing to the severe or critical stage, and so can play a significant role in the decrease and cure of Covid-19.
Covid-19 originally erupted in the central city of Wuhan in China Jan and Feb 2020, thousands of patients were infected within days, and all hospitals were rapidly overloaded with cases. As no effective medical treatment could be confirmed from conventional western medical experience, and there existed positive experience in the use of herbs in the successful treatment of SARS in 2003 [1, 2, 3], doctors began treating patients with herbal medicines in the temporary hospitals (Fangcang Hospitals) which were reconstructed from arenas and exhibitions. More than 90% of patients were successfully treated after being given Chinese herbal medicine prescribed to prevent patients with Covid-19 in the minor or ordinary stages from progressing to the severe or critical stage, and herbal medicine was able to rescue many severe and critical cases in ICU’s of hospitals as well. So, authorities in China issued national treatment guidelines [4] for Covid-19 introducing Chinese herbal medicine as the main therapy, to be given to patients as early as possible. This is a key point in explaining how control of Covid-19 was so quickly achieved in China.
TCM in an integrated way with conventional medicine, with conventional medicine used alone. Their results showed that the integrative approach decreased time to resolution of symptoms, to fever-clearance, and length of hospital stay; additionally the integrative approach increased the rates of clinical and radiological improvement, and also reduced the proportion of ordinary and minor cases which progressed to the severe form [5].
Covid-19 has been erupting and prevailing throughout the UK since the latter half of March 2020, when the Government introduced the first Lockdown phase. Although we have had to close complementary and alternative medicine clinics during this special time, the author still received many enquiries by remote forms of access, such as WeChat, WhatsApp, email, text messaging and so on daily, as a volunteer TCM consultant introduced by the overseas TCM forum and the Chinese Embassy in the UK (London). Many patients could not be admitted into hospitals or clinics for necessary medical treatment, although some nevertheless manifested quite typical and severe symptoms of Covid-19, and so had to be managed using the diagnostic methods of the TCM approach, and herbal treatments sent out to help them. A summary of the treatment method used is given here.
Necessary diagnostic procedures: clinical information is collected from patients, focusing on these aspects:
The history of exposure to Covid-19: Is there a history of contact with a Covid-19 infected person? If there is a history of possible contact, greater weight and attention is given to the patient’s clinical symptoms.
Clinical symptoms: Typical: fever, chills, cough, chest pain, breathlessness, even dyspnoea;
Atypical: anorexia, loss of taste or smell, diarrhea, chest or upper back pain, red and swollen toes, blurred vision etc.
Tongue appearance:
The tongue body is used for determining how long the virus has been active within the body, and assessing the strength of the virus’ resistance: for example, if the tongue is pale in color, this shows a sufferer who has been infected for a few of days and who has had stomach weakness in the past. If the tongue is red in color, this shows a sufferer who may have been infected for more than a week, or has manifested higher fever, or has suffered greater stress in the past, or has a stronger constitution.
Tongue coating:
The presence of a greasy coating can indicate Covid-19 infection;
The color of the greasy coating, from white to yellow, identifies the severity of the heat inside the body;
The thickness of the greasy coating identifies the severity of the Covid-19 infection. The thicker and more greasy the coating, the more severe the infection may be judged to be.
The tongue appearance provides unique and significant information from within the patient’s body, following TCM’s diagnostic approach.
Scientific diagnostic items: PCR, SaO₂, Blood tests and CT scan. If patients have been admitted by the NHS, or accepted by their GP, these necessary examinations should have been carried out; some patients may possess a finger pulse oximeter for reading SaO₂ by self-examination at home.
If anyone checks positive for at least two items amongst 1.1, 1.2 and 1.3, especially the greasy tongue coating which is a unique and significant sign for our diagnosis, we may assess them as infected or suspected patients with Covid-19, who should be given Chinese herbal medicine for treatment. While it is harder for us to obtain blood, PCR and CT scan results, the necessary examinations of 1.4 can confirm a diagnosis.
Herbal medicine treatment:
Because patients could not be seen face to face, we were unable to use acupuncture as a treatment, and Chinese herbal medicine was thus our only available treatment method. Some regulatory restrictions exist on the use of herbal medicine in UK, but we were able to use herbs and relevant formulae for treating Covid-19 as below:
For patients with infected and suspected Covid-19 in the early stage:
These patients display minor fever, shivering, minor cough, anorexia, loss of smell and taste, loose bowel movements, or dizziness, fatigue, general muscle aches etc. Pale or light red tongue with thin greasy coating.
Pattern of TCM: dampness accumulated in the lung;
Treatment principle: releasing excessive dampness.
The typical basic formula is Huoxiangzhengqi Decoction:
With the above herbs as the main formula, we make modifications according to the particular characteristics of an individual case, and produce a prescription of 120-150g of raw herbs which is decocted as herbal juice, half taken twice daily, one packet for each day; or we can also prepare them as herbal powders for drinking with warm water, twice daily.
For patients infected with or suspected of Covid-19 in the ordinary stage:
These patients manifest: fever and chills with a higher temperature, sometimes absent, chest tenderness or pain, breathlessness, more or less phlegm, dyspnea; or back-pain, painful, swollen toes or other symptoms. Red, or light red tongue with thick greasy, white-greasy, or yellow-greasy coating.
Pattern of TCM: excessive heat and dampness are accumulated in lungs;
Treatment principle: expel excessive heat and dampness;
The typical basic formula is Qingfeipaidu Decoction: (National guideline in China)
* denotes herbs forbidden for use in the UK, so herbs with similar effects had to be substituted. We selected relevant herbs or formulae as appropriate for individual prescriptions, replacing forbidden herbs.
Using the above herbs as the main formula, we made modifications according to the particular demands of an individual case, producing a prescription of 120-150g of raw herbs a day decocted as herbal juice, half to be taken twice daily.
* There are many herbs in this prescription in the original formulation. We don’t use all of these herbs in this formula in general in the UK, we select 12-15 herbs to make a suitable prescription according to the individual’s condition, following the treatment principles of the formula.
For people who need to be given double protection:
People who may have minor clinical symptoms, such as feeling only some throat discomfort, shivering and are easily fatigued, but may be particularly vulnerable to Covid-19:
Medical staff or carers in daily or frequent contact with Covid-19 patients;
Family members, relatives and close friends of Covid-19 sufferers;
Seniors with chronic or severe respiratory or cardiovascular disease.
Treatment principle: promote protective Qi and release wind-dampness
The herbal tea bags of protective formula are as below:
Above herbal powders are made into tea bags, 1 tea bag once daily.
48 cases are here collected and summarized from patients with infected or suspected Covid-19 whom I have treated, and for whom I have kept complete clinical records:
General state:
Sex: Female: 27, Male: 21;
Age: eldest: 71; youngest: 11months;
Grouped by age: 0—24 yrs. 6
25---45 yrs. 22
46—64 yrs.10
65—70 yrs.8
>71yrs.2
Diagnosed state of Covid-19 infection:
21 cases confirmed with a diagnosis of Covid-19 by a positive PCR (polymerase chain reaction) test;
27 suspected cases who manifested relevant symptoms, but without PCR test results*;
*patients could not easily obtain a PCR test during the first lockdown phase, and some were also wary of being officially diagnosed with an infectious disease at that stage.
State of treatment with Chinese herbal medicine:
28 cases who took the decocted raw herbal prescriptive form;
5 cases who took the herbal powder prescriptive form;
37 cases who took the protective herbal tea bags.*
*Some cases manifesting only minor symptoms were treated with herbal tea bags only. Typical Covid-19 sufferers with fever and other more severe symptoms were given a dry herbal prescription for the first one to two weeks, and then given herbal tea bags once the acute symptoms had been controlled or had much decreased.
None of those taking herbal treatment deteriorated to become Covid-19 sufferers in the severe or critical-severe stages; all were stabilized or improved.
None of those taking only the protective herbal tea bag treatment went on to become full Covid-19 sufferers.
Those discharged from hospital still in a state of severe ill-health were able to recover fully with TCM treatment.
Case 1:
Mrs. L, 38 year-old house-wife in London
After her husband had been admitted into ICU in hospital, she became feverish, chilly, suffered persistent coughing for a week without help, temp. 38.3°C, chest pain with breathlessness, anxiety, panic attacks, depression, nausea, anorexia and insomnia. She suffered from chronic gastritis, with a weak constitution. Pale tongue with white greasy coating.
Diagnosis: suspected Covid-19 in Cold-damp epidemic disease
Differentiation of syndrome: Cold-damp accumulated in the lungs with Spleen deficiency
Treating principle: warming cold and eliminating damp;
strengthening spleen and calming the mind.
Prescription: modified Huoxiangzhengqi combined with modified Wendan decoction (g):
Huoxiang 10, Houpo 10, Fuling 10, Banxia 10, Kouren 10, Sharen 10, Yiyiren 30, Huashi 15, Chenpi 10, Baizhu 10, Zhuru 10, Ganjiang 10, Gancao 5.
(Wendan provides needed mind-calming herbs, but strongly damp-expelling herbs were omitted because of the existing spleen deficiency and diarrhea)
Result: While taking herbs, she had some diarrhea, but was advised to keep taking the herbs until this stopped naturally; her tongue-coating cleared as well. She recovered after 2 weeks, but her husband died in hospital. She had a blood test which confirmed raised IgE and IgM levels after two weeks suffering Covid-19. A further two weeks of treatment with protective herbal tea bags was prescribed to complete her return to health, but he is told that her husband died in the hospital.
Case1 tongue appearance:
Case2:
Dr Z, 28; working as a junior doctor in UCLH
Temp. 39°- 40°C for 3 days with fatigue, tenderness and pain in the chest and breathlessness. She recognized she was suffering from Covid-19. She was worsening while taking only Paracetamol for treatment. Her worried mother sought help on her behalf from TCM.
Diagnosis: Covid-19;
TCM Differential Diagnosis by Syndrome: Damp & Heat accumulated in the lungs
Prescription: Lianhuaqingwen decoction:
Jiyinhua 10, Lianqiao 10, Xiangru 10, Xingren 10, Shigao 30,
Guanzhong 10, Yuxingcao 10, Dahuang 10, Huoxiang 10, Daqingye 10,
Bohe 5, Gancao 5.
(Lianhuaqingwen is a formula for Covid-19 treatment introduced by the National Health Authority in China – see ref vi.)
Result: her temperature fell to 37.3°-37.4°C over the next day, and she recovered sufficiently in a week to return to work.
Case 3: Ms. B, 58 year-old clinical manager:
She suffered a fever of 39°-40°C with coughing and chest pain for a week, with breathlessness, dyspnea, constipation and insomnia. She did not want to go to hospital although she realized she might have Covid-19. Red tongue with a yellow cracked coating.
Diagnosis: a high suspicion of Covid-19 infection.
TCM Differentiation of Syndromes: Phlegm with damp and heat accumulated in the lungs; Obstruction in the large intestine
Prescription: Qingfeipaidu Decoction variation
Jiangbanxia 15, Chenpi 10, Huangqin 10, Gualou 10, Zhuru 10, Dahuang 10 (Later),
Laifuzi 10, Yuxingcao 10, Daqingye 10, Zhuling 10, Fuling 10, Zexie 10, Tinglizi 10,
Huoxiang 10, Gancao 5.
Result: her temperature gradually decreased and she improved daily over a week. After she recovered, she showed less coating on her tongue. She was given a further two weeks of herbal tea bags to complete her recovery.
Case 4: Mr. W 71, a visitor to London, a retired engineer from Shanghai, China:
He and his wife came to London to visit their daughter’s family, but he became infected in April and was admitted into ICU as his SpO₂ fell to 83, with fever, severe breathlessness, chest pain and dyspnea. After having been discharged from ICU after one week his SpO₂ was still low at around 89-91 with breathlessness, nightmares, open mouth while sleeping; fatigue, difficulty in walking, unable to move more than 10 mins in the flat or climb stairs. Tongue: red tongue with teeth marks at sides and white greasy coating
Diagnosis: Post-Covid-19 syndrome
TCM Differentiation of Syndromes: Qi and Yin deficiency with unclear phlegm-heat;
Prescription: Jiangbanxia 15, Chenpi 10, Fuling 10, Huangqin 10, Daqingye 10,
Xuanshen 10, Beishashen 10, Maimendong 10, Chunalianzi 10,
Gualou 10, Baihe 10, Taizishen 30, Gancao 5
Result: The above herbal prescription was varied each week for a month, as he gradually recovered. His SpO2 increased to 95-96 in both wrists, he could walk down to and around his yard and return back up 4 flights of stairs to his flat without any palpitations, he experienced good sleep, regular bowel movements and a healthy color of complexion, lips and nails.
Chinese herbal medicine is an effective therapy to treat Covid-19. The 90
Chinese herbal medicine is an effective therapy for the treatment of Covid-19.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
