lancet-header

Preprints with The Lancet is part of SSRN´s First Look, a place where journals identify content of interest prior to publication. Authors have opted in at submission to The Lancet family of journals to post their preprints on Preprints with The Lancet. The usual SSRN checks and a Lancet-specific check for appropriateness and transparency have been applied. Preprints available here are not Lancet publications or necessarily under review with a Lancet journal. These preprints are early stage research papers that have not been peer-reviewed. The findings should not be used for clinical or public health decision making and should not be presented to a lay audience without highlighting that they are preliminary and have not been peer-reviewed. For more information on this collaboration, see the comments published in The Lancet about the trial period, and our decision to make this a permanent offering, or visit The Lancet´s FAQ page, and for any feedback please contact preprints@lancet.com.

Trends in Caesarean Section Rate According to Robson Group Classification Among Pregnant Women with SARS-CoV-2 Infection: A Single-Center Large Cohort Study in Italy

29 Pages Posted: 7 Feb 2022

See all articles by Angelo Sirico

Angelo Sirico

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Luigi Carbone

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Luisa Avino

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Cira Buonfantino

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Maria Chiara De Angelis

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Marco Di Cresce

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Annamaria Fabozzi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Antonietta Legnante

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Carla Riccardi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Romina Santoro

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Roberta Vallone

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Brunella Zizolfi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Antonio Riccardo Buonomo

CSEF - University of Naples Federico II - Department of Clinical Medicine and Surgery

Serena Salomè

CSEF - University of Naples Federico II - Section of Pediatrics

Francesco Raimondi

CSEF - University of Naples Federico II - Section of Pediatrics

Giuseppe Bifulco

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

Maurizio Guida

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences

More...

Abstract

Background: Since there is no available data on the trends of caesarean section (CS) rates in pregnant women with COVID-19 through the pandemic, we aimed to analyse the trends in caesarean section rate in a large cohort of pregnant women with COVID-19 according to the Robson Ten Group Classification System of deliveries.

Methods: We prospectively enrolled pregnant women with diagnosis of COVID-19 who delivered in our Center between March 2020 and November 2021. Deliveries were classified according to Robson group classification and according to three time periods: 1) deliveries from March 2020 to December 2020; 2) deliveries from January 2021 to April 2021; 3) deliveries from May 2021 to November 2021.We compared pregnancy characteristics and incidence of caesarean section according to the Robson category in the total population and according to the three time periods.

Findings: We included in our analysis 457 patients matching the inclusion criteria . We found that overall CS rate significantly decreased over time from period 1 to period 3 (152/222, 68.5% vs 81/134, 60.4% vs 58/101, 57.4%, χ 2 =4.261, p=0.039). CS rate significantly decreased over time in Robson category 1 (48/80, 60% vs 27/47,57.4% vs 8/24, 33.3%, χ2 =4.097, p=0.043) and Robson category 3 (13/42, 31% vs 6/33, 18.2% vs 2/22, 9.1%, χ2 =4.335, p=0.037). We also found that incidence of induction of labor significantly increased over time (8/222, 3.6% vs 12/134, 9% vs 11/101, 10.9%, χ2 =7.245, p=0.027).

Interpretation Our data provide an overview of the temporal changes in the management and obstetric outcome of COVID-19 pregnant women through the pandemic, confirming that working in a high-volume referral center for COVID-19 in pregnancy improved standards of obstetrical assistance over time.

Funding: None to declare.

Declaration of Interest: Authors declare no conflict of interest

Ethical Approval: The study has been approved by local IRL (Protocol #145/20, approved on April 3, 2020)

Keywords: SARS-CoV-2, COVID-19, pregnancy, cesarean section, Robson classification

Suggested Citation

Sirico, Angelo and Carbone, Luigi and Avino, Luisa and Buonfantino, Cira and De Angelis, Maria Chiara and Di Cresce, Marco and Fabozzi, Annamaria and Legnante, Antonietta and Riccardi, Carla and Santoro, Romina and Vallone, Roberta and Zizolfi, Brunella and Buonomo, Antonio Riccardo and Salomè, Serena and Raimondi, Francesco and Bifulco, Giuseppe and Guida, Maurizio, Trends in Caesarean Section Rate According to Robson Group Classification Among Pregnant Women with SARS-CoV-2 Infection: A Single-Center Large Cohort Study in Italy. Available at SSRN: https://ssrn.com/abstract=4011901 or http://dx.doi.org/10.2139/ssrn.4011901

Angelo Sirico (Contact Author)

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Luigi Carbone

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Luisa Avino

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Cira Buonfantino

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Maria Chiara De Angelis

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Marco Di Cresce

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Annamaria Fabozzi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Antonietta Legnante

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Carla Riccardi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Romina Santoro

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Roberta Vallone

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Brunella Zizolfi

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Antonio Riccardo Buonomo

CSEF - University of Naples Federico II - Department of Clinical Medicine and Surgery ( email )

Via S. Pansini 5
Naples, 80131
Italy

Serena Salomè

CSEF - University of Naples Federico II - Section of Pediatrics ( email )

Naples, 80131
Italy

Francesco Raimondi

CSEF - University of Naples Federico II - Section of Pediatrics ( email )

Naples, 80131
Italy

Giuseppe Bifulco

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy

Maurizio Guida

CSEF - University of Naples Federico II - Department of Neurosciences, Reproductive and Odontostomatological Sciences ( email )

Naples
Italy