Red cell distribution width, a predictive factor in immunocompromised patients with COVID-19: A comparison retrospective study between cancer and kidney transplant patients


Submitted: 30 April 2022
Accepted: 21 May 2022
Published: 20 June 2022
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Authors

  • Minoosh Moghimi Department of Internal Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.
  • Manijeh Jozpanahi Department of Infectious Disease, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.
  • Kasra Khodadadi Department of Internal Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.
  • Seyede Pegah Saeed School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.
  • Seyede Vanoushe Azimi Pirsaraie School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.
  • Nooshin Jalili Department of Internal Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, Islamic Republic of.

We aimed to review the records of cancer and kidney transplant patients of out of 1135 COVID-19 patients, who were referred to our hospital (Valiasr) in Zanjan, from March 16th, 2020, to June 11th, 2020. This was single-center, historical cohort study. Patients were divided into different subgroups and compared of disease outcomes. The only predictor of death was lactate dehydrogenase (LDH). The rate of red cell distribution width (RDW) in patients with active cancer was higher than kidney transplant patients and was statistically significant. There was no statistically significant difference in mortality between active and non-active cancer groups. Female sex and low SpO2 has increased the chances of ICU admission. Patients with active cancer generally have severe and more complicated disease and RDW can be a predictable option.


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