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    Infect Chemother. 2022 Mar;54(1):182-182. English.
    Published online Mar 03, 2022.
    https://doi.org/10.3947/ic.2022.0020
    Copyright © 2022 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS
    letter

    Aseptic Meningitis and mRNA Coronavirus Disease 2019 Vaccine

    Rujittika Mungmunpuntipantip,1 and Viroj Wiwanitkit2
      • 1Private Academic Consultant, Bangkok, Thailand.
      • 2Honorary professor, Dr DY Patil University, Pune, India.
    • Corresponding Author: Rujitika Mungmunpuntipantip, PhD. Private Academic Consultant, 26 Bangkok 111, 101800, Thailand. Tel: +66-273778788, Email: rujittika@gmail.com
    Received February 08, 2022; Accepted February 17, 2022.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Dear Editor:

    We would like to share ideas on the publication “Aseptic meningitis following second dose of an mRNA coronavirus disease 2019 vaccine in a healthy male: case report and literature review [1]”. Kang et al. described a case and speculated on a possible clinical link. We agree that coronavirus disease 2019 (COVID-19) immunization has the potential to cause side effects, with neurological problems being a potential risk. The vaccine recipient in this case developed meningitis, but there is no information on the patient’s immune/neruological state prior to inoculation. As a result, concluding a clinical relationship may be challenging. Recognize the likelihood of a concurrent medical condition in a COVID-19 vaccine recipient that could lead to neurological problems. Concurrent dengue infection is possible [2], and it may be the cause of aseptic meningitis [3].

    Notes

    Funding:None.

    Conflict of Interest:No conflict of interest.

    Author Contributions:

    • Conceptualization: RM, VW.

    • Data curation: RM, VW.

    • Formal analysis: RM, VW.

    • Funding acquisition: RM, VW.

    • Investigation: RM, VW.

    • Methodology: RM, VW.

    • Project administration: RM, VW.

    • Resources: RM, VW.

    • Software: RM, VW.

    • Supervision: VW.

    • Validation: RM, VW.

    • Visualization: RM, VW.

    • Writing - original draft: RM .

    • Writing - review & editing: RM, VW.

    References

      1. Kang HS, Kim JE, Yoo JR, Oh H, Kim M, Kim YR, Heo ST. Aseptic Meningitis Following Second Dose of an mRNA Coronavirus Disease 2019 Vaccine in a Healthy Male: Case Report and Literature Review. Infect Chemother 2022;54:189–194.
      1. Kebayoon A, Wiwanitkit V. Dengue after COVID-19 vaccination: Possible and might be missed. Clin Appl Thromb Hemost 2021;27:10760296211047229
      1. García-Rivera EJ, Vorndam V, Rigau-Pérez JG. Use of an enhanced surveillance system for encephalitis and aseptic meningitis for the detection of neurologic manifestations of dengue in Puerto Rico, 2003. P R Health Sci J 2009;28:114–120.
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    MeSH Terms
    COVID-19 Vaccines*
    COVID-19*
    Coronavirus*
    Meningitis, Aseptic*
    RNA, Messenger*
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