Clin Exp Vaccine Res. 2021 Sep;10(3):292-292. English.
Published online Sep 30, 2021.
© Korean Vaccine Society.
letter

Shingles and mRNA COVID‐19 vaccine

Rujittika Mungmunpuntipantip,1 and Viroj Wiwanitkit2,*
    • 1Private Academic Consultant Center, Bangkok, Thailand.
    • 2Dr DY Patil University, Pune, India.
Received August 19, 2021; Revised September 04, 2021; Accepted September 06, 2021.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Dear Editor

We would like to share ideas on “A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect?” [1]. Aksu and Öztürk [1] concluded “Although the exact reason remains unsolved, vaccine-induced immunomodulation ...vaccines may be responsible mechanisms for the reactivation of herpes zoster.” The adverse event following mRNA vaccination is an important consideration at present. For zoster lesions, the underlying pathogenesis is interesting. Due to the lack of laboratory investigation on immunological profiles and skin pathological study, it is difficult to conclude the immunopathological process. There are many zoster-like lesions. In general, a concurrent coronavirus disease 2019 and zoster are possible [2]; therefore, zoster might be only a coincidence in the post-vaccination period. The epidemiological study might give a clue but the exact pathogenesis should be by standard pathological study.

References

    1. Aksu SB, Ozturk GZ. A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect? Clin Exp Vaccine Res 2021;10:198–201.
    1. Loh J, Tham SM, Tambyah PA, Yan G, Lee CK, Chai LY. Range of varicella zoster co-infections with COVID-19, Singapore. Infect Chemother 2021;53:391–394.

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