The Present and FutureJACC Review Topic of the WeekClinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week
JACC Review Topic of the Week
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Central Illustration
Key Words
ACE inhibitor
angiotensin-converting enzyme-2
angiotensin II receptor blockers
COVID-19
mineralocorticoid receptor antagonist
SARS-CoV-2
Abbreviations and Acronyms
ACE
angiotensin-converting enzyme
ACE2
angiotensin-converting enzyme 2
ADAM 17
disintegrin and metalloprotease 17
Ang 1-7
angiotensin 1-7
Ang I
angiotensin I
Ang II
angiotensin II
ARB
angiotensin II receptor blocker
ARDS
acute respiratory distress syndrome
AT1
angiotensin II type I receptor
AT2
angiotensin II type II receptor
ERK
extracellular signal-regulated kinase
ET
endothelin
IL
interleukin
MAPK1
mitogen-activated protein kinase 1
MRAs
mineralocorticoid receptor antagonists
RAS
renin-angiotensin system
rhACE2
recombinant angiotensin-converting enzyme 2
SARS-CoV-2
severe acute respiratory-syndrome coronavirus-2
TACE
tumor necrosis factor α-converting enzyme
TNF
tumor necrosis factor
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