Artificial intelligence enabled non-invasive T-ray imaging technique for early detection of coronavirus infected patients

https://doi.org/10.1016/j.imu.2022.101025Get rights and content
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Abstract

A new artificial intelligence (AI) supported T-Ray imaging system designed and implemented for non-invasive and non-ionizing screening for coronavirus-affected patients. The new system has the potential to replace the standard conventional X-Ray based imaging modality of virus detection. This research article reports the development of solid state room temperature terahertz source for thermograph study. Exposure time and radiation energy are optimized through several real-time experiments. During its incubation period, Coronavirus stays within the cell of the upper respiratory tract and its presence often causes an increased level of blood supply to the virus-affected cells/inter-cellular region that results in a localized increase of water content in those cells & tissues in comparison to its neighbouring normal cells. Under THz-radiation exposure, the incident energy gets absorbed more in virus-affected cells/inter-cellular region and gets heated; thus, the sharp temperature gradient is observed in the corresponding thermograph study. Additionally, structural changes in virus-affected zones make a significant contribution in getting better contrast in thermographs. Considering the effectiveness of the Artificial Intelligence (AI) analysis tool in various medical diagnoses, the authors have employed an explainable AI-assisted methodology to correctly identify and mark the affected pulmonary region for the developed imaging technique and thus validate the model. This AI-enabled non-ionizing THz-thermography method is expected to address the voids in early COVID diagnosis, at the onset of infection.

Keywords

Avalanche transit time device
Coronavirus disease
Large-signal impedance and admittance study
Non-linear quantum drift-diffusion simulator
Room temperature characteristics
Terahertz source and radiation system
T-ray thermograph study

Abbreviations

AI- Artificial Intelligence
COVID- Corona Virus Disease
SARS-CoV-2- Severe Acute Respiratory Syndrome Coronavirus 2
THz- Terahertz
Tray- Terahertz Ray
CT Scan- Computed Tomography Scan
FEM-finite element method
CNN- Convolution Neural Network
ATT- Avalanche Transit Time
SNR-signal-to-noise ratio
RCNN- Region-Based Convolutional Neural Network
RPN- Region Proposal Network
RoI- Regions of Interest
FBP- Full Body Prosthetics
ConvNet- Convolutional Network
aLaRa- as Low as Reasonably achievable

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