Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
A Case of Severe COVID-19-related Pneumonia Seven Years after Heart Transplantation
Gentaro TaniguchiShouji MatsushimaTakeo FujinoToru HashimotoKeisuke ShinoharaHiroshi KisanukiKayo MisumiShunsuke KatsukiAkira ShioseKohtaro Abe
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 5254-25

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Abstract

A 67-year-old man on intense immunosuppressive therapy after heart transplantation for end-stage hypertrophic cardiomyopathy 7 years ago developed severe dyspnea and was admitted to our hospital. His serum SARS-CoV-2 antigen test was positive, and he was diagnosed with COVID-19-related pneumonia. He was started on ventilatory management for severe respiratory failure and remdesivir for COVID-19, with careful adjustment of immunosuppressive drugs. However, unexpectedly prolonged muscle weakness necessitated transfer to a rehabilitation facility. Although the COVID-19 pandemic has subsided, it is still considered a risk in post-transplant cases. Infection control is considered critical in heart transplant recipients, especially in those receiving intensified immunosuppressive drugs.

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© 2025 by The Japanese Society of Internal Medicine

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