The influence of social isolation on the incidence of positivity in covid-19 tests in a metropolitan region of São Paulo, Brazil

Authors

  • Alexandre José Natário aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Glaucia Luciano da Veiga aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Vagner Loduca Lima cDepartamento de Oftalmologia. Centro Universitário FMABC – Santo André, Brasil.
  • Thaís Gascón aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • José Claudio dos Santos Pinheiro gDepartamento de Data Science, Escola Superior de Propaganda e Marketing (ESPM) – São Paulo, Brasil.
  • Joyce Regina Santos Raimundo aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Beatriz da Costa Aguiar Alves aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Matheus Moreira Perez aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Claudia Giorgia Bronzatti de Oliveira Rodrigues aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Aleksandra Vanessa Lambiasi Sant’Anna aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Marina Cristina Peres aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Katharyna Cardoso de Gois aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil.
  • Lysien Ivania Zambrano eDepartment of Morphological Sciences, School of Medical, Sciences, Universidad Nacional Autónoma de Honduras (UNAH) - Tegucigalpa, Honduras.
  • Marcia Aparecida Sperança bUniversidade Federal do ABC - São Bernardo do Campo, Brasil.
  • Geraldo Reple Sobrinho dSecretaria da Saúde de São Bernardo do Campo. Prefeitura Municipal de São Bernardo do Campo - Brasil.
  • Fernando Luiz Affonso Fonseca aLaboratório de Análises Clínicas. Centro Universitário FMABC – Santo André, Brasil; fDepartamento de Ciências Farmacêuticas. Universidade Federal de São Paulo/UNIFESP – Diadema, Brasil.

DOI:

https://doi.org/10.36311/jhgd.v31.12656

Keywords:

coronavirus disease 2019, social isolation, laboratory, outcome, Brazil

Abstract

Introduction: With the arrival of the SARS-CoV-2 (Coronavirus 2 of severe acute respiratory syndrome) pandemic in Brazil, especially in the city of São Paulo, there was a need to apply social isolation policies associated with testing, covering all municipalities. The Clinical Analysis Laboratory of Centro Universitário FMABC was one of the first laboratories to receive certification and qualification to perform RT-PCR (reverse transcriptase reaction followed by polymerase chain reaction) tests in the metropolitan region of São Paulo.

Objective: Aim to analyze the influence of adopting social isolation on the incidence of positivity in COVID-19 tests in the metropolitan region of São Paulo, Brazil.

Methods: a descriptive study carried out from March to May 2020, epidemiological data were collected from each unit served and organized by the data controllership team of the Clinical Analysis Laboratory of FMABC. Epidemiological, demographic, and laboratory data were extracted from the Matrix® outpatient data management system. Clinically suspected cases and confirmed by laboratory tests (RT-PCR and serological tests) were entered. The tests were divided into serological tests using the RT-PCR molecular test, on samples of nasopharyngeal mucosal scrapings collected with sterile Swab.

Results: It were evaluated PCR test and antibody presence (IgA, IgM and IgG) in blood samples of 16.297 patients. 22.718 tests were performed for the diagnosis of COVID-19, both RT-PCR (10.410 tests) and serological tests to detect anti-SARS-CoV-2 antibodies, IgA, IgM and IgG, a total of 16.297 patients were assessed, 63% women and 37% men. It was observed that the social isolation policies adopted during this period contained the massive expansion of contamination, at least while the social isolation rates were above 55%.

Conclusion: The data of this study demonstrated the effectiveness of social isolation in containing the positive contamination of SARS-CoV-2 in the metropolitan region of São Paulo, at least for the first three months.

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Published

2021-12-01

Issue

Section

ORIGINAL ARTICLES