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Accepted for/Published in: JMIR Formative Research

Date Submitted: Nov 19, 2021
Date Accepted: Feb 7, 2022
Date Submitted to PubMed: Feb 22, 2022

The final, peer-reviewed published version of this preprint can be found here:

How Vaccine Ambivalence Can Lead People Who Inject Drugs to Decline COVID-19 Vaccination and Ways This Can Be Addressed: Qualitative Study

Aronson ID, Bennett AS, Ardouin-Guerrier MA, Rivera-Castellar G, Gibson B, Santoscoy S, Vargas-Estrella B

How Vaccine Ambivalence Can Lead People Who Inject Drugs to Decline COVID-19 Vaccination and Ways This Can Be Addressed: Qualitative Study

JMIR Form Res 2022;6(3):e35066

DOI: 10.2196/35066

PMID: 35191841

PMCID: 8945077

How vaccine ambivalence can lead people who inject drugs to decline COVID-19 vaccination, and ways this can be addressed: a Qualitative Study

  • Ian David Aronson; 
  • Alex S. Bennett; 
  • Mary-AndrĂ©e Ardouin-Guerrier; 
  • German Rivera-Castellar; 
  • Brent Gibson; 
  • Sam Santoscoy; 
  • Brittney Vargas-Estrella

ABSTRACT

Background:

People who inject drugs (PWID) are disproportionately impacted by SARS-CoV-2 and COVID-19, yet frequently do not accept vaccinations against SARS-CoV-2 when offered.

Objective:

To explore why PWID decline free vaccinations against SARS-CoV-2, and how barriers to vaccination can potentially be addressed.

Methods:

We conducted semi-structured qualitative interviews with 17 unvaccinated adult PWID during August and September 2021, at a New York City syringe service program.

Results:

Participants acknowledged they faced increased risk from SARS-CoV-2 due to their injection drug use, but feared long term substance use may have weakened their health, making them especially vulnerable to side effects. Fears of possible side effects, compounded by widespread medical mistrust and questions about the overall value of vaccination contributed to significant ambivalence among our sample.

Conclusions:

Community-developed messages are needed in outreach efforts to explain the importance of vaccination, including the far greater dangers of COVID-19 compared to possible unintended side effects. Messages delivered by trusted community members explaining their own decisions to vaccinate, and emphasizing vaccines’ ability to prevent inadvertently infecting loved ones, may help increase uptake. Community focused messaging strategies, like those used to increase HIV/HCV testing and overdose prevention among PWID, may prove similarly effective.


 Citation

Please cite as:

Aronson ID, Bennett AS, Ardouin-Guerrier MA, Rivera-Castellar G, Gibson B, Santoscoy S, Vargas-Estrella B

How Vaccine Ambivalence Can Lead People Who Inject Drugs to Decline COVID-19 Vaccination and Ways This Can Be Addressed: Qualitative Study

JMIR Form Res 2022;6(3):e35066

DOI: 10.2196/35066

PMID: 35191841

PMCID: 8945077

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