2022 年 96 巻 5 号 p. 215-218
Herein, we report the case of a 69-year-old Japanese woman who was admitted to our hospital with dyspnea and severe hypoxia. She was diagnosed as having COVID-19 with ARDS. At the same time, her HIV screening test result also returned positive. However, the results of confirmatory tests for HIV, including Western blot analysis and RNA PCR were negative. Finally, the patient was diagnosed as having a false-positive result of the HIV screening test due to cross-reactivity between HIV gp41 antigen and SARS-CoV-2 antibody; similarity between HIV and SARS-CoV-2 spike proteins could yield false-positive results of HIV screening. Our case implies the importance of recognizing the possibility of a false-positive result of HIV screening in patients with COVID-19.