open access

Vol 5, No 4 (2020)
Research paper
Published online: 2020-10-28
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Can hematological and biochemical parameters fasten the diagnosis of COVID-19 in emergency departments?

Burak Katipoğlu1, Leyla Öztürk Sönmez2, Hülya Vatansev3, Nalan Yüce1, Mustafa Sabak4, Lukasz Szarpak567, Togay Evrin1
·
Disaster Emerg Med J 2020;5(4):175-181.
Affiliations
  1. Department of Emergency Medicine, Ufuk University Medical Faculty, Ankara, Türkiye
  2. Department of Emergency Medicine, Beyhekim State Hospital, Konya, Türkiye
  3. Department of Chest Diseases, Meram Medical Faculty, Necmettin Erbakan University, Konya, Türkiye
  4. Department of Emergency Medicine, Nizip State Hospital, Gaziantep, Türkiye
  5. Department of Emergency Medicine, Maria Sklodowska-Curie Medical Academy, Warsaw, Poland
  6. Department of Emergency Medicine, Polish Society of Disaster Medicine, Warsaw, Poland
  7. Department of Emergency Medicine, Comprehensive Cancer Center in Bialystok, Bialystok, Poland

open access

Vol 5, No 4 (2020)
ORIGINAL ARTICLES
Published online: 2020-10-28

Abstract

INTRODUCTION: The primary aim of the study was to compare the laboratory and radiological parameters of COVID-19 positive and negative patients confirmed by Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR), and Chest Computed Tomography (CCT) of patients admitting with the suspicion of COVID-19. The secondary purpose of the study was to find objective parameters to speed up the clinician for further examination, treatment or referral decision in COVID-19 suspicion.

MATERIAL AND METHODS: A total of 61 COVID-19 suspected patients were evaluated in the study. Swab samples were taken for RT-PCR analysis. CCT was taken for 42 patients who described dyspnea. According to CCT and RT-PCR results, the patient population was divided into 2 groups as COVID-19 positive group (n = 32); and COVID-19 negative group (n = 29). Between two groups; demographic, clinical, laboratory and radiological parameters were compared.

RESULTS: Male gender (p = 0.03), PLR value (p = 0.021) and CO-RADS scores were higher in the COVID-19 positive group. Oxygen saturation (SaO2) (p = 0.027) and PCT, WBC, Neutrophil count, Lymphocyte count values were significantly low in COVID-19 positive group (p = 0.03, p = 0.001, p = 0.017, p = 0.021, respectively). PLR showed a positive correlation with fever, CRP, neutrophil count and NLR, which are indicators of inflammation.

CONCLUSIONS: SaO2, WBC, lymphocyte count, neutrophil count and low PCT levels, and PLR elevation showed a significant difference in COVID-19 patients in our retrospective cohort study examining the Turkish population. We believe that these results will allow clinicians to make quick decisions in patient management more simply.

Abstract

INTRODUCTION: The primary aim of the study was to compare the laboratory and radiological parameters of COVID-19 positive and negative patients confirmed by Real-Time Reverse Transcription Polymerase Chain Reaction (RT-PCR), and Chest Computed Tomography (CCT) of patients admitting with the suspicion of COVID-19. The secondary purpose of the study was to find objective parameters to speed up the clinician for further examination, treatment or referral decision in COVID-19 suspicion.

MATERIAL AND METHODS: A total of 61 COVID-19 suspected patients were evaluated in the study. Swab samples were taken for RT-PCR analysis. CCT was taken for 42 patients who described dyspnea. According to CCT and RT-PCR results, the patient population was divided into 2 groups as COVID-19 positive group (n = 32); and COVID-19 negative group (n = 29). Between two groups; demographic, clinical, laboratory and radiological parameters were compared.

RESULTS: Male gender (p = 0.03), PLR value (p = 0.021) and CO-RADS scores were higher in the COVID-19 positive group. Oxygen saturation (SaO2) (p = 0.027) and PCT, WBC, Neutrophil count, Lymphocyte count values were significantly low in COVID-19 positive group (p = 0.03, p = 0.001, p = 0.017, p = 0.021, respectively). PLR showed a positive correlation with fever, CRP, neutrophil count and NLR, which are indicators of inflammation.

CONCLUSIONS: SaO2, WBC, lymphocyte count, neutrophil count and low PCT levels, and PLR elevation showed a significant difference in COVID-19 patients in our retrospective cohort study examining the Turkish population. We believe that these results will allow clinicians to make quick decisions in patient management more simply.

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Keywords

CBC, COVID-19, CO-RADS, PLR, RT-PCR

About this article
Title

Can hematological and biochemical parameters fasten the diagnosis of COVID-19 in emergency departments?

Journal

Disaster and Emergency Medicine Journal

Issue

Vol 5, No 4 (2020)

Article type

Research paper

Pages

175-181

Published online

2020-10-28

Page views

837

Article views/downloads

717

DOI

10.5603/DEMJ.a2020.0039

Bibliographic record

Disaster Emerg Med J 2020;5(4):175-181.

Keywords

CBC
COVID-19
CO-RADS
PLR
RT-PCR

Authors

Burak Katipoğlu
Leyla Öztürk Sönmez
Hülya Vatansev
Nalan Yüce
Mustafa Sabak
Lukasz Szarpak
Togay Evrin

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