Research progress of severe acute respiratory syndrome coronavirus 2 on aerosol collection and detection

https://doi.org/10.1016/j.cclet.2023.108378Get rights and content

Abstract

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019 has negatively affected people's lives and productivity. Because the mode of transmission of SARS-CoV-2 is of great concern, this review discusses the sources of virus aerosols and possible transmission routes. First, we discuss virus aerosol collection methods, including natural sedimentation, solid impact, liquid impact, centrifugal, cyclone and electrostatic adsorption methods. Then, we review common virus aerosol detection methods, including virus culture, metabolic detection, nucleic acid-based detection and immunology-based detection methods. Finally, possible solutions for the detection of SARS-CoV-2 aerosols are introduced. Point-of-care testing has long been a focus of attention. In the near future, the development of an instrument that integrates sampling and output results will enable the real-time, automatic monitoring of patients.

Graphical abstract

In this review, research progress of severe acute respiratory syndrome coronavirus 2 on aerosol collection and detection are summarized, and the process of collecting and detecting is shown.

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Keywords

Virus aerosol
Aerosol transmission
Aerosol collection
Aerosol detection
Protective measure

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