Short Communication
Lung volume reduction and infection localization revealed in Big data CT imaging of COVID-19

https://doi.org/10.1016/j.ijid.2020.10.095Get rights and content
Under a Creative Commons license
open access

Highlights

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    Analysis of massive CT lung image among COVID-19, CAP, and nonpneumonia subjects.

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    Significantly reduced lung volume was found in COVID-19 patients.

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    Significantly increased lung mass and density were found in COVID-19 patients.

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    The infections of COVID-19 patients tend to present as bilateral lower lobes.

Abstract

The ongoing worldwide COVID-19 pandemic has become a huge threat to global public health. Using CT image, 3389 COVID-19 patients, 1593 community-acquired pneumonia (CAP) patients, and 1707 nonpneumonia subjects were included to explore the different patterns of lung and lung infection. We found that COVID-19 patients have a significant reduced lung volume with increased density and mass, and the infections tend to present as bilateral lower lobes. The findings provide imaging evidence to improve our understanding of COVID-19.

Keywords

COVID-19
Community-Acquired pneumonia
Non-Pneumonia subjects
Lung
Big data

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© 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.