Comparison between Suspected and Confirmed COVID-19 Respiratory Patients: What Is beyond the PCR Test
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Data Collection
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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COVID-19 Confirmed | COVID-19 Suspected | p-Value | |
---|---|---|---|
N | 50 | 103 | |
Age (mean (SD)) | 67.02 (10.98) | 66.68 (17.52) | 0.900 |
Sex = M/F n (%) | 33/17 (66.0/34.0) | 57/46 (55.3/44.7) | 0.279 |
Smoking n (%) | <0.001 | ||
Never | 18 (47.4) | 33 (63.5) | |
Former | 1 (2.6) | 12 (23.1) | |
Active | 19 (50.0) | 7 (13.5) | |
Comorbidities = N/Y n (%) | 12/38 (24.0/76.0) | 18/85 (17.5/82.5) | 0.462 |
Fever = N/Y n (%) | 4/46 (8.0/92.0) | 70/33 (68.0/32.0) | <0.001 |
Temperature (°C) (mean (SD)) | 37.36 (0.82) | 36.69 (0.90) | <0.001 |
Dyspnea = N/Y n (%) | 7/43 (14.0/86.0) | 41/62 (39.8/60.2) | 0.002 |
Cough = N/Y n (%) | 27/23 (54.0/46.0) | 69/34 (67.0/33.0) | 0.167 |
CT positive = N/Y n (%) | 11/39 (22.0/78.0) | 57/46 (55.3/44.7) | <0.001 |
Pleural effusion = N/Y n (%) | 44/6 (88.0/12.0) | 61/42 (59.2/40.8) | 0.001 |
D-dimer (ng/mL) (median [IQR]) | 558.50 [503.50, 1010.25] | 1360.00 [770.00, 3285.50] | 0.375 |
Lymphocytes (%) (median [IQR]) | 10.30 [5.10, 14.20] | 13.70 [8.00, 22.55] | 0.006 |
CPR (mg/L) (median [IQR]) | 136.70 [76.15, 203.10] | 21.82 [3.56, 67.16] | <0.001 |
LDH (mu/mL) (median [IQR]) | 436.00 [356.50, 523.75] | 257.00 [208.25, 373.50] | <0.001 |
Respiratory Failure = N/Y n (%) | 20/30 (40.0/60.0) | 70/33 (68.0/32.0) | 0.002 |
OR | CI(95%) | p-Value | |
---|---|---|---|
CPR | 1.02 | 0.11, 1.02 | <0.001 |
CT positive | 11.43 | 3.01, 43.3 | <0.001 |
Pleural effusion | 0.15 | 0.04, 0.63 | 0.009 |
Dyspnea | 10.48 | 2.08, 52.7 | 0.004 |
Respiratory Failure | 5.84 | 1.73, 19.75 | 0.002 |
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Principe, S.; Grosso, A.; Benfante, A.; Albicini, F.; Battaglia, S.; Gini, E.; Amata, M.; Piccionello, I.; Corsico, A.G.; Scichilone, N. Comparison between Suspected and Confirmed COVID-19 Respiratory Patients: What Is beyond the PCR Test. J. Clin. Med. 2022, 11, 2993. https://doi.org/10.3390/jcm11112993
Principe S, Grosso A, Benfante A, Albicini F, Battaglia S, Gini E, Amata M, Piccionello I, Corsico AG, Scichilone N. Comparison between Suspected and Confirmed COVID-19 Respiratory Patients: What Is beyond the PCR Test. Journal of Clinical Medicine. 2022; 11(11):2993. https://doi.org/10.3390/jcm11112993
Chicago/Turabian StylePrincipe, Stefania, Amelia Grosso, Alida Benfante, Federica Albicini, Salvatore Battaglia, Erica Gini, Marta Amata, Ilaria Piccionello, Angelo Guido Corsico, and Nicola Scichilone. 2022. "Comparison between Suspected and Confirmed COVID-19 Respiratory Patients: What Is beyond the PCR Test" Journal of Clinical Medicine 11, no. 11: 2993. https://doi.org/10.3390/jcm11112993