Short Communication
COVID-19 disease severity is linked to host immunity as well as lung and gut dysbiosis: a narrative review

https://doi.org/10.1016/j.jgar.2021.10.009Get rights and content
Under a Creative Commons license
open access

Highlights

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    COVID-19 disease severity is strongly linked to host viral immunity.

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    Host viral immunity is affected by the lung and gut microbiome.

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    Monocyte dysfunction in aging plays an essential role in the progression of COVID-19 disease.

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    The lung and gut microbiome may be a potential therapeutic target for COVID-19.

Keywords

COVID-19
SARS-CoV-2
Pneumonia
Lung and gut dysbiosis
Gut–lung axis
Monocyte dysfunction

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© 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.