Predicting the dynamical behavior of COVID-19 epidemic and the effect of control strategies

https://doi.org/10.1016/j.chaos.2021.110823Get rights and content

Highlights

  • The SEIR model has been used to capture the behavior of COVID-19 infectious disease.

  • Disease-free equilibrium of COVID-19 disease is investigated.

  • Endemic equilibrium of COVID-19 is investigated.

  • The effects of different control strategies on the equilibrium are predicted.

Abstract

This paper uses transformed subsystem of ordinary differential equation seirsmodel, with vital dynamics of birth and death rates, and temporary immunity (of infectious individuals or vaccinated susceptible) to evaluate the disease-free DFEX¯DFE,and endemic EEX¯EE equilibrium points, using the Jacobian matrix eigenvalues λi of both disease-free equilibrium X¯DFE, and endemic equilibrium X¯EE for COVID-19 infectious disease to show S, E, I, and R ratios to the population in time-series. In order to obtain the disease-free equilibrium point, globally asymptotically stable (R01), the effect of control strategies has been added to the model (in order to decrease transmission rateβ, and reinforce susceptible to recovered flow), to determine how much they are effective, in a mass immunization program. The effect of transmission rates β (from S to E) and α (from R to S) varies, and when vaccination effectρ, is added to the model, disease-free equilibrium X¯DFE is globally asymptotically stable, and the endemic equilibrium pointX¯EE, is locally unstable. The initial conditions for the decrease in transmission rates of β and α, reached the corresponding disease-free equilibrium X¯DFE locally unstable, and globally asymptotically stable for endemic equilibriumX¯EE. The initial conditions for the decrease in transmission ratesβandα, and increase in ρ, reached the corresponding disease-free equilibrium X¯DFE globally asymptotically stable, and locally unstable in endemic equilibriumX¯EE.

Keywords

COVD-19
Pandemic
SEIRS model
Prediction
Dynamical Behavior
Vaccination

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