Dengue Fever and COVID-19 Co-Infection at the Emergency Department of a Tertiary Care Hospital in Jeddah, Saudi Arabia
  • Abdalla Khalil
    International Medical Centre Hospital, Jeddah, Saudi Arabia; King’s College trust PRUH, London, UK http://orcid.org/0000-0001-6853-0284
  • Badr Badr
    International Medical Centre Hospital, Jeddah, Saudi Arabia
  • Harry Wright
    King’s College trust PRUH, London, UK
  • Mohammed Talo
    International Medical Centre Hospital, Jeddah, Saudi Arabia
  • Mohammad Atteiya
    International Medical Centre Hospital, Jeddah, Saudi Arabia

Keywords

Dengue fever, COVID-19 infection, thrombocytopenia, clinical outcome

Abstract

Introduction: Co-infection with COVID-19 and other viral or bacterial infections has been described in many studies. Most cases of dengue fever in Saudi Arabia have been reported in Jeddah city and mainly during the summer season.

Method and results: We describe four patients who presented to the emergency department with febrile illness accompanied by symptoms and blood tests suggestive of dengue fever. They also had radiological findings suggestive of COVID-19 chest infection and positive PCR tests. Three of the patients required hospital admission, and all had a good outcome.

Conclusion: In areas with a high rate of dengue fever, serological screening for dengue fever should be considered as part of COVID-19 investigation, especially if symptoms or a full blood count are suggestive.

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References

  • Lansbury L, Lim B, Baskaran V, Lim WS. Co-infections in people with COVID-19: a systematic review and meta-analysis. J Infect2020;81(2):266–275.
  • Centers for Disease Control and Prevention. Dengue around the world. Available from https://www.cdc.gov/dengue/areaswithrisk/around-the-world.html (accessed 7 December 2020).
  • Babiker T, Rasitha Banu GM, Bashier I, Hajmeeral M. Incidence rate of dengue fever in Saudi Arabia 2011-2018, a retrospective. Int J Recent Technol Eng 2019;8(4S5).
  • Badreddine S, Al-Dhaheri F, Al-Dabbagh A, Al-Amoudi A, Al-Ammari M, Elatassi N, et al. Dengue fever. Clinical features of 567 consecutive patients admitted to a tertiary care center in Saudi Arabia. Saudi Med J 2017;38(10):1025–1033.
  • Azhar E, Kao M, Niedrig M, Masri B, Godus A, Badierah R. Virological diagnosis of dengue fever in Jeddah, Saudi Arabia: comparison between RT-PCR and virus isolation in cell culture. Infect Dis Immun 2010;2(2):24–29.
  • Hegazi MA, Bakarman MA, Alahmadi TS, Butt NS, Alqahtani AM, Aljedaani BS, et al. Risk factors and predictors of severe dengue in Saudi population in Jeddah, Western Saudi Arabia: a retrospective study. Am J Trop Med Hyg 2020;102(3):613–621.
  • Yang X, Yang Q, Wang Y, Wu Y, Xu J, Yu Y, et al. Thrombocytopenia and its association with mortality in patients with COVID-19. J Thromb Haemost 2020;18(6):1469–1472.
  • Lippi G, Plebani M, Henry BM. Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis. Clin Chim Acta 2020;506:145–148.
  • Verduyn M, Allou N, Gazaille V, Andre M, Desroche T, Jaffar MC, et al. Co-infection of dengue and COVID-19: a case report. PLoS Negl Trop Dis 2020;14(8):e0008476.
  • Centers for Disease Control and Prevention. Dengue. Diagnosis. Available from https://www.cdc.gov/dengue/healthcare-providers/diagnosis (accessed 7 December 2020).
  • Ahmed NH, Broor S. Comparison of NS1 antigen detection ELISA, real time RT-PCR and virus isolation for rapid diagnosis of dengue infection in acute phase. J Vector Borne Dis 2014;51(3):194199.

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    Published: 2020-12-28
    Issue: 2020: Vol 7 No 12 (view)

    How to cite:
    1.
    Khalil A, Badr B, Wright H, Talo M, Atteiya M. Dengue Fever and COVID-19 Co-Infection at the Emergency Department of a Tertiary Care Hospital in Jeddah, Saudi Arabia. EJCRIM 2020;7 doi:10.12890/2020_002167.