SARS‐CoV‐2 Non-Structural Protein 1(NSP1) Mutation Virulence and Natural Selection: Evolutionary Trends in the Six Continents
26 Pages Posted: 20 Oct 2022
Abstract
We analyzed about 6.5 million samples E87D as the most frequent mutation on NSP1 affects on destabilization of the virusE87D mutation has signed up to January 2022 as the first frequent mutation observed. H110Y and R24C are the second and third most frequent mutations, respectively.
Keywords: COVID-19, SARS-CoV-2, NSP1, mutations, translational inhibition, E87D
Suggested Citation: Suggested Citation
Ghaleh, Samira Salami and Rahimian, Karim and Mahmanzar, Mohammadamin and Mahdavi, Bahar and Tokhanbigli, Samaneh and Mollapour Sisakht, Mahsa and Farhadi, Amin and Bakhtiari, Mahsa Mousakhan and Kuehu, Donna Lee and Deng, Youping, SARS‐CoV‐2 Non-Structural Protein 1(NSP1) Mutation Virulence and Natural Selection: Evolutionary Trends in the Six Continents. Available at SSRN: https://ssrn.com/abstract=4246887 or http://dx.doi.org/10.2139/ssrn.4246887
Feedback
Feedback to SSRN
If you need immediate assistance, call 877-SSRNHelp (877 777 6435) in the United States, or +1 212 448 2500 outside of the United States, 8:30AM to 6:00PM U.S. Eastern, Monday - Friday.