Microcirculatory hemodynamic indexes (HI) were assessed in patients with moderate and severe COVID-19. In both groups, a significant increase in the absolute spectral indexes (HI1, HI2, and HI3) and the ratio of low-frequency to high-frequency component (HI1/HI3) was revealed. In the group of severe infection, only the “slow” index (low-frequency HI1) of microcirculatory hemodynamics was significantly lower. The oscillatory indices MAYER1-3 and RESP1-3 were reduced in patients of both groups. The aggravation of the disease course was accompanied by depression of the low-frequency index HI1. Regulatory shifts compensate for disturbances in microcirculatory processes in moderate COVID-19, but severe course was associated with their decompensation.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 171, No. 4, pp. 463-468, April, 2021
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Kuznik, B.I., Smolyakov, Y.N., Shapovalov, Y.K. et al. The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19. Bull Exp Biol Med 171, 453–457 (2021). https://doi.org/10.1007/s10517-021-05248-7
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DOI: https://doi.org/10.1007/s10517-021-05248-7