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Early Detection of Exacerbation of the Severe Acute Respiratory Syndrome Coronavirus 2 Infection using Fitbit (DEXTERITY Pilot Study)
Kan Yamagami;
Akihiro Nomura;
Mitsuhiro Kometani;
Masaya Shimojima;
Kenji Sakata;
Soichiro Usui;
Kenji Furukawa;
Masayuki Takamura;
Masaki Okajima;
Kazuyoshi Wataname;
Takashi Yoneda
ABSTRACT
Background:
Some patients with coronavirus disease 2019 (COVID-19) experienced sudden death because of sudden symptom deterioration. Thus, an alarm system that could detect early signs of COVID-19 exacerbation beforehand, to prevent serious illness or death of patients while receiving outpatient treatment at home or in hotels is necessary.
Objective:
Here, we tested whether estimated oxygen variations (EOV), a relative physiological scale that represents users’ blood oxygen saturation level during sleep measured by Fitbit, predicted COVID-19 symptom exacerbation.
Methods:
Study period was from August to November 2020. We enrolled 23 COVID-19 patients diagnosed by SARS-CoV-2 polymerase chain reaction-positive (mean age ± standard deviation, 50.9 ± 20 years; 70% female), let each patient wore the Fitbit for 30 days.
Results:
COVID-19 symptoms were exacerbated in 6 (26%). High EOV signal (a patient’s oxygen level exhibits significant dip and recovery within the index period) had 80% sensitivity before symptom exacerbations, whereas resting heart rate signal only had 50% sensitivity. Coincidental obstructive sleep apnea syndrome confirmed by polysomnography was detected in a patient by consistently high EOV signals.
Conclusions:
This pilot study successfully detected early COVID-19 symptoms exacerbation by measuring EOV and may help to identify early signs of COVID-19 exacerbation. Clinical Trial: We registered this study with the University Medical Information Network Clinical Trial Registry (UMIN000041421).
Citation
Please cite as:
Yamagami K, Nomura A, Kometani M, Shimojima M, Sakata K, Usui S, Furukawa K, Takamura M, Okajima M, Wataname K, Yoneda T
Early Detection of Symptom Exacerbation in Patients With SARS-CoV-2 Infection Using the Fitbit Charge 3 (DEXTERITY): Pilot Evaluation