Predictors of recovery from COVID-19: a retrospective study in one of the aspirational district of India
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20213803Keywords:
COVID-19, Aspirational, Epidemiology, Recovery predictors, Kaplan Meier, RegressionAbstract
Background: Coronavirus disease 2019 (COVID-19) is the third corona virus that has emerged among the human population in last two decades. The main aim of this study was to describe the epidemiology and recovery predictors of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients admitted at COVID health facilities.
Methods: A retrospective observational study was conducted from April 2020 to September 2020. The categorical and continuous variables were expressed as frequency, percentages and as mean and standard deviation respectively. Pearson chi square test and multivariable logistic regression were applied to ascertain the associations. Mean recovery time was compared by Kaplan-Meier analysis.
Results: The mean age of participants was 36.8±17.54 years with a male preponderance. The age group of 20-39 years was the most affected group (43%). Age and pre-existing co morbidities were found to be significant factors affecting the recovery duration of patients. Mean recovery time with respect to age groups and gender was 15 and 18 days respectively. Mortality rate of 2% was recorded.
Conclusions: In conclusion, COVID-19 affects a wide-range of population. Although age was not found to be a significant factor for acquiring the disease, however younger age group was significantly associated with early recovery. Considering our findings, we suggest additional measures to protect the vulnerable population.
References
Sun J, He W, Wang L, Lai A, Ji X, Zhai X, et al. COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives. Trends Mol Med. 2020;26(5):483-95.
Nikpouraghdam M, Jalali Farahani A, Alishiri GH, Heydari S, Ebrahimnia M, Samadinia H, et al. Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. J Clin Virol. 2020;127.
Sharma E, Katoch G, Guleri R, Bhardwaj J. Characteristics of patients infected with SARS COVID-19 admitted at COVID health facilities in one of the aspirational district of India: a retrospective study. Int J Community Med Public Heal. 2020;7(11):4435.
World Health Organization. Novel Coronavirus Disease (COVID-19) Situation Report- 46/ 2020. https://www.who.int/india/emergencies/india-situation-report. Accessed on 10th May, 2021.
COVID-19 pandemic in Himachal Pradesh. 2020. https://en.wikipedia.org/wiki/COVID-19_pandemic _in_Himachal_Pradesh. Accessed on 10th May, 2021.
Government of India Ministry of Health & Family Welfare. Guidelines for Home Isolation of very mild/pre-symptomatic COVID-19 cases. 2020.
Livingston E, Bucher K. Coronavirus Disease 2019 (COVID-19) in Italy. JAMA - J Am Med Assoc. 2020;323(14):1335.
Sotgiu G, Gerli AG, Centanni S, Miozzo M, Canonica GW, Soriano JB, et al. Advanced forecasting of SARS-CoV-2-related deaths in Italy, Germany, Spain, and New York State. Allergy Eur J Allergy Clin Immunol. 2020;75(7):1813-5.
Gupta N, Agrawal S, Ish P, Mishra S, Gaind R, Usha G, et al. Clinical and epidemiologic profile of the initial COVID-19 patients at a tertiary care centre in India. Monaldi Arch Chest Dis. 2020;90(1):193-6.
Chen T, Wu D, Chen H, Yan W, Yang D, Chen G, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: Retrospective study. BMJ. 2020;368:1-14.
Bienvenu LA, Noonan J, Wang X, Peter K. Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities. Cardiovasc Res. 2020;116(14):2197-206.
Das AK, Gopalan SS. Epidemiology of CoVID-19 and predictors of recovery in the Republic of Korea. medRxiv. 2020;2020:1-6.
Barman MP, Rahman T, Bora K, Borgohain C. COVID-19 pandemic and its recovery time of patients in India: A pilot study. Diabetes Metab Syndr Clin Res Rev. 2020;14(5):1205-11.
AL-Rousan N, AL-Najjar H. Data analysis of coronavirus COVID-19 epidemic in South Korea based on recovered and death cases. J Med Virol. 2020;92(9):1603-8.
Government of India Ministry of Health & Family Welfare. Revised guidelines for Home Isolation of very mild/pre-symptomatic/asymptomatic COVID-19 cases. 2020. https://www.mohfw.gov.in /pdf/RevisedHomeIsolationGuidelines.pdf. Accessed on 10th May, 2021.