COVID-19 – Associated Acute Transverse Myelitis in Children: A Case Report and Review of Literature

Naseri, Maryam; Ashrafzadeh, Farah; Khademi, Gholamreza; Imannezhad, Shima; Sorouri, Shahabaddin; Sezavar, Majid

doi:10.32598/jpr.10.SpecialIssue.992.2

Volume 10 - Special Issue J. Pediatr. Rev 2022, 10 - Special Issue: 433-438 | Back to browse issues page

‎ 10.32598/jpr.10.SpecialIssue.992.2

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Naseri M, Ashrafzadeh F, Khademi G, Imannezhad S, Sorouri S, Sezavar M. COVID-19 – Associated Acute Transverse Myelitis in Children: A Case Report and Review of Literature. J. Pediatr. Rev 2022; 10 :433-438
URL: http://jpr.mazums.ac.ir/article-1-430-en.html

COVID-19 – Associated Acute Transverse Myelitis in Children: A Case Report and Review of Literature

Maryam Naseri¹

, Farah Ashrafzadeh¹

, Gholamreza Khademi²

, Shima Imannezhad³

, Shahabaddin Sorouri⁴

, Majid Sezavar

⁵

1- Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Pediatric Intensivist, Neonatal Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
3- Department of Pediatric Neurology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Internal Department, Mashhad University of Medical Sciences, Mashhad, Iran.
5- Assistant Professor of Pediatric Intensive Care, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran. , Sezavardm@mums.ac.ir

Abstract: (1641 Views)

Background: Several studies have reported neurological manifestations and complications related to specific coronavirus genotypes, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this study, we examined one of the rare clinical manifestations of Coronavirus disease 2019 (COVID-19), which was one of the first cases of acute transverse myelitis in children in the world.
Case presentation: This case report was dedicated to a little girl with COVID-19 admitted with weakness, lethargy, and constipation. Her magnetic resonance imaging (MRI) showed signal changes accompanied by edema. The patient did not show an optimal response to the methylprednisolone succinate and intravenous human immunoglobulins (IVIG) and experienced cardiorespiratory arrest. The patient was eventually discharged with partial recovery in limb power.
Conclusions: his study demonstrates the importance of rapid diagnosis and treatment of the sequelae of COVID-19 infections.

Keywords: Acute transverse myelitis, Children, COVID-19, SARS-CoV-2

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Type of Study: Case Report and Review of Literature | Subject: Pediatric Infectious Diseases
Received: 2021/08/17 | Accepted: 2021/10/18 | Published: 2022/01/1

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