Elsevier

IDCases

Volume 27, 2022, e01380
IDCases

Case report
Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient

https://doi.org/10.1016/j.idcr.2022.e01380Get rights and content
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Abstract

Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prolonged glucocorticoid administration with poor outcome likely due to adrenal involvement.

Keywords

Cryptococcus neoformans
COVID-19
Glucocorticoids
Fungemia
Meningoencephalitis

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