Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

This article has now been updated. Please use the final version.

Delayed Vasovagal Reaction with Reflex Syncope Following Covid-19 Vaccination
Bonpei TakaseKatsumi HayashiSatoko TakeiTetsuya HisadaNobuyuki MasakiMasayoshi Nagata
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 9318-21

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Abstract

Coronavirus disease 2019 (COVID-19) has become a pandemic, and vaccines remain the only effective tools available for ending it. However, their side effects, such as syncope, which mimics sudden cardiac death, are serious concerns. We herein report 6 cases of delayed vasovagal syncope and presyncope (VVR) caused by COVID-19 vaccination among 25,530 COVID-19 patients. The prevalence of delayed VVR due to COVID-19 vaccination was 0.026%. In addition, no delayed VVR was found among 17,386 patients who received the influenza vaccine. Delayed VVR is likely to be overlooked if medical staff are not aware of this symptom. This report provides significant information regarding effects of COVID-19 vaccination.

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© 2022 by The Japanese Society of Internal Medicine
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