Pregnancy Outcome in First 50 SARS-Cov-2 Positive Patients at Our Center

Abstract

OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. Various studies have reported adverse pregnancy outcomes in SARS-CoV-2 infection. This study aimed to evaluate the maternal and fetal outcomes in SARS-CoV-2 affected pregnancies at our set up.

STUDY DESIGN: It was a prospective cohort study conducted at a tertiary care Army Hospital, India. The first 50 cases of SARS CoV-2 positive pregnant women and 144 suspected cases that were found SARS-CoV-2 negative, received and managed at separate set up, during a period extending from 01 April 2020 to 15 Sep 2020 were included in our study. Their obstetric and neonatal outcomes along with the demographic and other clinical data were compared.

RESULTS: Total RT-PCR positivity rate of SARS-CoV-2 infection in pregnant women was 2.7%. 96% of our patients were asymptomatic for SARS-CoV-2 infection. Premature rupture of membrane, preterm delivery, and NICU admission was similar in both groups. There were increased incidences (70%) of cesarean section in SARS-CoV-2 positive pregnant women.

CONCLUSION: The study reported comparable maternal and fetal outcomes in SARS-CoV 2 positive pregnant women when compared with SARS-CoV-2 negative pregnant women.