The Changes in Trends of Lower Gastrointestinal Endoscopy Conducted in Children and Adolescents after the COVID-19 Outbreak in Korea
Abstract
:1. Introduction
2. Methods
2.1. Patients and Study Design
2.2. Statistical Analysis
2.3. Ethics Statement
3. Results
3.1. Baseline Characteristics of the Patients
3.2. Comparison of Characteristics between the Pre- and PostCOVID-19 Era
3.3. Comparison of Characteristics between Patients Receiving Colonoscopies and Sigmoidoscopies
3.4. Factors Associated with Conducting a Colonoscopy over a Sigmoidoscopy
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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n (%) (n = 1307) | |
---|---|
Male | 805 (61.6) |
Age at LGI endoscopy (years) | 15.0 (11.0–17.0) |
Height (cm) | 160.4 (142.5–170.0) |
Weight (kg) | 50.8 (34.7–60.2) |
BMI (kg/m2) | 19.0 (16.6–21.8) |
Year of first LGI endoscopy | |
2016 | 263 (20.1) |
2017 | 277 (21.2) |
2018 | 270 (20.7) |
2019 | 283 (21.7) |
2020 | 213 (16.3) |
LGI endoscopy type | |
Colonoscopy | 1041 (79.6) |
Sigmoidoscopy | 266 (20.4) |
Sedation/Anesthesia type | |
Intravenous sedation | 1235 (94.5) |
General anesthesia | 8 (0.6) |
None | 64 (4.9) |
n (%) (n = 1307) | |
---|---|
Gastrointestinal bleeding | 494 (37.8) |
Chronic diarrhea | 463 (35.4) |
Abdominal pain | 262 (20.0) |
Weight loss | 22 (1.7) |
Perianal discharge | 19 (1.5) |
Growth retardation | 18 (1.4) |
Anemia | 13 (1.0) |
Foreign body removal | 7 (0.5) |
Vomiting | 4 (0.3) |
Lip pigmentation | 2 (0.2) |
Hypoalbuminemia | 1 (0.1) |
Fever of unknown origin | 1 (0.1) |
Oral ulcer | 1 (0.1) |
Colonoscopy (n = 1044) | Sigmoidoscopy (n = 263) | Total (n = 1307) | |
---|---|---|---|
Normal | 402 (38.5) | 85 (32.3) | 487 (37.3) |
Crohn’s disease | 273 (26.1) | 9 (3.4) | 282 (21.6) |
Non-specific colitis | 134 (12.8) | 74 (28.1) | 208 (15.9) |
Ulcerative colitis | 98 (9.4) | 29 (11.0) | 127 (9.7) |
Colorectal polyps | 60 (5.7) | 18 (6.8) | 78 (6.0) |
EGID | 26 (2.5) | 6 (2.3) | 32 (2.4) |
Pseudomembranous colitis | 4 (0.4) | 16 (6.1) | 20 (1.5) |
Hemorrhoids | 15 (1.4) | 2 (0.8) | 17 (1.3) |
Allergic colitis | 0 (0.0) | 12 (4.6) | 12 (0.9) |
Foreign body | 4 (0.4) | 3 (1.1) | 7 (0.5) |
Proctitis | 6 (0.6) | 1 (0.4) | 7 (0.5) |
GVHD | 1 (0.1) | 4 (1.5) | 5 (0.4) |
Diverticulum/Diverticulitis | 4 (0.4) | 0 (0.0) | 4 (0.3) |
Solitary rectal ulcer | 3 (0.3) | 1 (0.4) | 4 (0.3) |
Angiodysplasia | 3 (0.3) | 0 (0.0) | 3 (0.2) |
Behcet’s disease | 3 (0.3) | 0 (0.0) | 3 (0.2) |
Sigmoid volvulus | 1 (0.1) | 2 (0.8) | 3 (0.2) |
Terminal ileitis | 3 (0.3) | 0 (0.0) | 3 (0.2) |
TB enterocolitis | 2 (0.2) | 0 (0.0) | 2 (0.2) |
Collagenous colitis | 1 (0.1) | 0 (0.0) | 1 (0.1) |
Ischemic colitis | 0 (0.0) | 1 (0.4) | 1 (0.1) |
Microvillous inclusion disease | 1 (0.1) | 0 (0.0) | 1 (0.1) |
PreCOVID-19 Era (n = 1093) | PostCOVID-19 Era (n = 214) | p-Value | |
---|---|---|---|
Indication in accordance to LGI guidelines | 0.261 | ||
Yes | 864 (79.0) | 177 (82.7) | |
No | 229 (21.0) | 37 (17.3) |
Colonoscopy (n = 1041) | Sigmoidoscopy (n = 266) | p-Value | |
---|---|---|---|
Male | 649 (62.3) | 156 (58.6) | 0.300 |
Age at diagnosis (years) | 15.2 (12.9–17.1) | 7.5 (2.5–15.6) | <0.001 |
Sedation/Anesthesia type | <0.001 | ||
Intravenous sedation | 1035 (99.4) | 200 (75.2) | |
General anesthesia | 5 (0.5) | 3 (1.1) | |
None | 1 (0.1) | 63 (23.7) | |
Indication: LGI bleeding | 326 (31.3) | 168 (63.2) | <0.001 |
Indication: chronic diarrhea | 417 (40.1) | 46 (17.3) | <0.001 |
Diagnosis: IBD | 374 (35.9) | 38 (14.3) | <0.001 |
Follow-up LGI endoscopy | 207 (19.9) | 34 (12.8) | 0.010 |
Univariate Analysis | Multivariate Analysis | |||
---|---|---|---|---|
OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
Sex (male vs. female) | 1.17 (0.89–1.53) | 0.269 | ||
Age at LGI endoscopy (years) | 1.23 (1.20–1.26) | <0.001 | 1.19 (1.12–1.27) | <0.001 |
Weight at LGI endoscopy (kg) | 1.06 (1.05–1.07) | <0.001 | 1.00 (0.99–1.02) | 0.773 |
LGI endoscopy performance year (post- vs. pre-COVID-19) | 1.77 (1.18–2.73) | 0.008 | 1.60 (1.00–2.63) | 0.058 |
Indication: LGI bleeding (yes vs. no) | 0.27 (0.20–0.35) | <0.001 | 0.56 (0.37–0.83) | 0.005 |
Indication: chronic diarrhea (yes vs. no) | 3.20 (2.29–4.54) | <0.001 | 1.35 (0.84–2.15) | 0.213 |
Diagnosis: IBD (yes vs. no) | 3.36 (2.36–4.92) | <0.001 | 1.80 (1.20–2.77) | 0.006 |
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Lee, S.W.; Kang, B.; Choi, S.; Choe, B.-H.; Kim, Y.B.; Lee, K.J.; Kim, H.J.; Jang, H.-J.; Choi, S.Y.; Yi, D.Y.; et al. The Changes in Trends of Lower Gastrointestinal Endoscopy Conducted in Children and Adolescents after the COVID-19 Outbreak in Korea. Medicina 2022, 58, 1378. https://doi.org/10.3390/medicina58101378
Lee SW, Kang B, Choi S, Choe B-H, Kim YB, Lee KJ, Kim HJ, Jang H-J, Choi SY, Yi DY, et al. The Changes in Trends of Lower Gastrointestinal Endoscopy Conducted in Children and Adolescents after the COVID-19 Outbreak in Korea. Medicina. 2022; 58(10):1378. https://doi.org/10.3390/medicina58101378
Chicago/Turabian StyleLee, Sang Woo, Ben Kang, Sujin Choi, Byung-Ho Choe, Yu Bin Kim, Kyung Jae Lee, Hyun Jin Kim, Hyo-Jeong Jang, So Yoon Choi, Dae Yong Yi, and et al. 2022. "The Changes in Trends of Lower Gastrointestinal Endoscopy Conducted in Children and Adolescents after the COVID-19 Outbreak in Korea" Medicina 58, no. 10: 1378. https://doi.org/10.3390/medicina58101378