Myopericarditis with Hemorrhagic Pericardial Effusion Following BNT162b2 mRNA COVID-19 Vaccine

8 Pages Posted: 22 Mar 2022

See all articles by Gabriela S. Generette

Gabriela S. Generette

University of Illinois College of Medicine

James Troyer

affiliation not provided to SSRN

Alice Hemenway

affiliation not provided to SSRN

Moamen Al Zoubi

affiliation not provided to SSRN

Abstract

Since the start of the pandemic, to date, around 200 million cases have been diagnosed with COVID-19 worldwide with an estimated 4.2 million death toll. Mass vaccination has taken place to control the spread of infection with the most commonly used vaccines being Pfizer-BioNTech and Moderna. However, the adverse events associated with vaccination have not been fully investigated. Of concern are some serious cardiovascular events such as myocarditis, pericarditis or perimyocarditis development post-vaccination. Hemorrhagic pericardial effusion has not been reported. We report a case of myopericarditis with a hemorrhagic pericardial effusion that developed two weeks following BNT162b2 mRNA COVID-19 vaccine. We performed a complete workup for the underlying cause without any significant findings. Our patient was treated with colchicine with ibuprofen, and he made full recovery. A follow-up cardiovascular magnetic resonance imaging (CMR) showed no signs of active inflammation.

Note:
Funding: None to declare.

Declaration of Interests: The authors report no conflicts of interest.

Patient Informed Consent Statement: The patient gave permission for this case to be published. The design of the work has been approved by the Mercyhealth Offices of Research Administration and Privacy.

Keywords: COVID-19, COVID-19 vaccine, myopericarditis, pericardial effusion, hemorrhagic pericardial effusion

Suggested Citation

S. Generette, Gabriela and Troyer, James and Hemenway, Alice and Al Zoubi, Moamen, Myopericarditis with Hemorrhagic Pericardial Effusion Following BNT162b2 mRNA COVID-19 Vaccine. Available at SSRN: https://ssrn.com/abstract=4028719 or http://dx.doi.org/10.2139/ssrn.4028719

Gabriela S. Generette (Contact Author)

University of Illinois College of Medicine ( email )

One Illini Drive
Peoria, IL 61605
United States

James Troyer

affiliation not provided to SSRN ( email )

No Address Available

Alice Hemenway

affiliation not provided to SSRN ( email )

No Address Available

Moamen Al Zoubi

affiliation not provided to SSRN ( email )

No Address Available

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