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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Case report
Coronavirus disease-19 (COVID-19) associated with acute necrotising pancreatitis (ANP)
  1. Naren K Kumaran,
  2. Biraj K Karmakar and
  3. Ormond M Taylor
  1. Department of General Surgery, Kettering General Hospital NHS Foundation Trust, Kettering, UK
  1. Correspondence to Dr Naren K Kumaran; narenkumar.kumaran{at}nhs.net

Abstract

Coronavirus is a severe infectious disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has led to increased mortality worldwide. Multiple reports have been published citing that gastrointestinal symptoms are common in patients with COVID-19 infection. It has also been found that the ACE2 receptor of SARS-CoV-2 is expressed more in the pancreas than the lungs. Despite this, little attention has been paid to the extent and details of pancreatic injury caused by COVID-19. Lack of awareness regarding the COVID-19 status of patients presenting with pancreatitis may expose healthcare workers to SARS-CoV-2 while performing interventions to manage complications of pancreatitis such as necrosis. We report a case of COVID-19-induced acute necrotising pancreatitis in the absence of any known risk factors.

  • gastrointestinal surgery
  • pancreatitis
  • global health
  • infectious diseases
  • general surgery

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2020-237903

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    Footnotes

    • NKK and BKK are joint first authors.

    • Twitter @bkk_27

    • NKK and BKK contributed equally.

    • Contributors NKK was involved in the acquisition, analysis, interpretation of the data and drafting of the article. BKK revised the article for important intellectual content and gave final approval of the version published. NKK and BKK agree to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved. OMT conceptualised the case report.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.