ReviewCurrent approaches used in treating COVID-19 from a molecular mechanisms and immune response perspective
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open access
Keywords
Coronavirus
SARS-CoV-2
Investigational medications
Pandemic
Pathophysiology
Viral immune response
Abbreviations
ACE2
angiotensin-converting enzyme 2
AHFS
American Hospital Formula Service
ANGII
angiotensin II
APCs
antigen presenting cells
ARDS
acute respiratory distress syndrome
COVID-19
coronavirus disease
CoVs
coronaviruses
GVHD
graft versus host disease
HCoVs
human coronoaviruses
IBV
infectious bronchitis coronavirus
IFN-γ
interferon-gamma
ILCs
innate lymphoid cells
MERS-CoV
Middle East respiratory syndrome
nsps
nonstructural proteins
NKs
natural killer cells
ORFs
open reading frames
PAMPs
pathogen-associated molecular patterns
RdRp
RNA-dependent RNA polymerase
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
SLE
systemic lupus erythematosus
TMPRSS2
transmembrane serine protease 2
WHO
World Health Organization
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Peer review under responsibility of King Saud University.
© 2020 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.