Elsevier

Radiology Case Reports

Volume 17, Issue 12, December 2022, Pages 4556-4560
Radiology Case Reports

Case Report
Isolated breast parenchymal changes following COVID-19 vaccine booster

https://doi.org/10.1016/j.radcr.2022.08.094Get rights and content
Under a Creative Commons license
open access

Abstract

Ipsilateral transient axillary lymphadenopathy is well-documented following COVID-19 mRNA vaccine administration. Recently, rare mammographic findings of breast tissue changes with co-existing lymphadenopathy have been documented. Current literature on isolated ipsilateral true breast parenchymal changes on diagnostic mammography in symptomatic patients following COVID-19 mRNA vaccine administration is limited. This is one of the first case reports that demonstrates isolated ipsilateral focal asymmetry 5 days after administration of COVID-19 mRNA vaccine followed by complete resolution of symptoms and focal asymmetry confirmed on follow up magnetic resonance imaging. These findings warrant the development of guidelines to reduce unnecessary invasive procedures as part of the workup for possible malignancy.

Keywords

Focal asymmetry
COVID-19
Breast
Mammography

Abbreviations

MRI
magnetic resonance imaging
CC
craniocaudal
MLO
mediolateral oblique
MIP
maximum intensity projection

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Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.