Antiviral Properties of Pennisetum purpureum Extract against Coronaviruses and Enteroviruses
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of Pennisetum purpureum Extract (Heyiya®)
2.2. Determination of Total Phenolic Content
2.3. Cell Lines and Viruses
2.4. In Vitro Cytotoxicity Assay
2.5. TCID50 Assay
2.6. Virus Inhibition Assay
2.7. Antiviral Effect of the P. purpureum Extract against IBV
2.8. Statistical Analysis
3. Results
3.1. Characterization of Pennisetum purpureum Extract
3.2. Cytotoxicity of Pennisetum purpureum Extract (Heyiya®)
3.3. Antiviral Effect of Pennisetum purpureum Extract (Heyiya®) against EV71
3.4. Antiviral Effect of Pennisetum purpureum Extract (Heyiya®) against FCoV
3.5. Antiviral Effect of Pennisetum purpureum Extract (Heyiya®) against PEDV
3.6. Antiviral Effect of Pennisetum purpureum Extract (Heyiya®) against IBV
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Extract Dilution | pH | Total Phenolic Content (TPC) mg/L Gallic Acid Equivalent (GAE) |
---|---|---|
1× | 5.3 | 1413.708 |
2× | 5.3 | 1328.513 |
4× | 5.3 | 1315.921 |
8× | 5.0 | 984.228 |
10× | 5.1 | 916.995 |
100× | 5.1 | 128.490 |
200× | 5.1 | 66.128 |
300× | 5.1 | 39.936 |
600× | 5.0 | 23.188 |
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Chen, Y.-N.; Kao, W.M.-W.; Lee, S.-C.; Wu, J.-M.; Ho, Y.-S.; Hsieh, M.-K. Antiviral Properties of Pennisetum purpureum Extract against Coronaviruses and Enteroviruses. Pathogens 2022, 11, 1371. https://doi.org/10.3390/pathogens11111371
Chen Y-N, Kao WM-W, Lee S-C, Wu J-M, Ho Y-S, Hsieh M-K. Antiviral Properties of Pennisetum purpureum Extract against Coronaviruses and Enteroviruses. Pathogens. 2022; 11(11):1371. https://doi.org/10.3390/pathogens11111371
Chicago/Turabian StyleChen, Yi-Ning, Wenny Mei-Wen Kao, Shu-Chi Lee, Jaw-Min Wu, Yi-Sheng Ho, and Ming-Kun Hsieh. 2022. "Antiviral Properties of Pennisetum purpureum Extract against Coronaviruses and Enteroviruses" Pathogens 11, no. 11: 1371. https://doi.org/10.3390/pathogens11111371