American Journal of Nursing Science

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Review: COVID-19 Outbreak and Diabetic Patient’s Treatments Close Relationship

Received: 12 October 2021    Accepted: 30 October 2021    Published: 17 November 2021
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Abstract

The severe acute respiratory syndrome (SARS-COV) are well known viruses from the family of Coronaviridae which in past caused outbreaks that led to various detrimental effect on world in many aspects. In the year 2019 when the new strain of coronavirus family (SARS-COV2) which is now known as COVID-19 (corona virus disease and 19 refer to the year it was first recognized) outbreak occurred in Wuhan affected the globe seriously. The health system got into a big challenge as this new strain of coronavirus spread much rapidly and caused much more mortality than the previous ones. The mortality was higher in those population which had comorbid conditions such as cardiovascular disease, lung disorders, chronic illnesses, diabetic patients and at the same time affected by COVID-19. Various regimes were selected but still proper and effective management is not available for such patients as these patients are already on multiple drugs. Among those chronic illnesses diabetic patients were found be highly susceptible to COVID-19. High disease mortality and worse outcomes in patients with diabetes urges that Diabetes appropriate management and better selection of drugs is crucial for the better outcomes in diabetic patients as most of the patients are treated for hypertension, hyperglycaemia and ongoing other chronic illnesses which could lead to worse case scenarios.

DOI 10.11648/j.ajns.20211006.11
Published in American Journal of Nursing Science (Volume 10, Issue 6, December 2021)
Page(s) 244-247
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Diabetes, ACEIs, Hyperglycemia

References
[1] Family - Coronaviridae, in Virus Taxonomy, A. M. Q. King, et al., Editors. 2012, Elsevier: San Diego. p. 806-828.
[2] Zhang, Z., The outbreak pattern of SARS cases in China as revealed by a mathematical model. Ecol Modell, 2007. 204 (3): p. 420-426.
[3] Oboho, I. K., et al., 2014 MERS-COV outbreak in Jeddah--a link to health care facilities. N Engl J Med, 2015. 372 (9): p. 846-54.
[4] Song, Z., et al., From SARS to MERS, Thrusting Coronaviruses into the Spotlight. Viruses, 2019. 11 (1).
[5] Huang, C., et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 2020. 395 (10223): p. 497-506.
[6] Onder, G., G. Rezza, and S. J. J. Brusaferro, Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. 2020.
[7] Guan, W.-j., et al., Clinical characteristics of coronavirus disease 2019 in China. 2020. 382 (18): p. 1708-1720.
[8] Zou, Q., et al., Influenza A-associated severe pneumonia in hospitalized patients: Risk factors and NAI treatments. 2020. 92: p. 208-213.
[9] Memish, Z. A., et al., Middle East respiratory syndrome. 2020.
[10] Remuzzi, A. and G. J. T. L. Remuzzi, COVID-19 and Italy: what next? 2020.
[11] Bode, B., et al., Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States. J Diabetes Sci Technol, 2020.
[12] Iacobellis, G., et al., Admission Hyperglycemia and Radiological findings of SARS-COV2 in patients with and without Diabetes. Diabetes Research and Clinical Practice, 2020.
[13] Ceriello, A., S. W. Zarich, and R. Testa, Lowering glucose to prevent adverse cardiovascular outcomes in a critical care setting. Journal of the American College of Cardiology, 2009. 53 (5 Supplement): p. S9-S13.
[14] Reily, C., et al., Glycosylation in health and disease. Nat Rev Nephrol, 2019. 15 (6): p. 346-366.
[15] Brufsky, A., Hyperglycemia, Hydroxychloroquine, and the COVID-19 Epidemic. Journal of Medical Virology, 2020.
[16] Drucker, D. J., Coronavirus Infections and Type 2 Diabetes—Shared Pathways with Therapeutic Implications. Endocrine Reviews, 2020. 41 (3).
[17] Verdecchia, P., et al., Angiotensin converting enzyme inhibitors and angiotensin receptor blockers in the treatment of hypertension: should they be used together? 2010. 8 (6): p. 742-746.
[18] Messerli, F. H., et al., Angiotensin-converting enzyme inhibitors in hypertension: to use or not to use? 2018. 71 (13): p. 1474-1482.
[19] Winkelmayer, W. C., et al., Underuse of ACE inhibitors and angiotensin II receptor blockers in elderly patients with diabetes. 2005. 46 (6): p. 1080-1087.
[20] Wan, Y., et al., Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus. 2020. 94 (7).
[21] Xu, X., et al., Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. 2020. 63 (3): p. 457-460.
[22] Li, X. C., J. Zhang, and J. L. J. P. r. Zhuo, The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases. 2017. 125: p. 21-38.
[23] Meng, J., et al., Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension. 2020. 9 (1): p. 757-760.
[24] Hsu, W.-T., et al., Effect of Renin-Angiotensin-Aldosterone System Inhibitors on Short-Term Mortality After Sepsis: A Population-Based Cohort Study. 2020. 75 (2): p. 483-491.
[25] Drucker, D. J. J. E. r., Coronavirus Infections and Type 2 Diabetes—Shared Pathways with Therapeutic Implications. 2020. 41 (3): p. bnaa011.
[26] Xianwei, W., et al., Cross-talk between inflammation and angiotensin II: studies based on direct transfection of cardiomyocytes with AT1R and AT2R cDNA. 2012. 237 (12): p. 1394-1401.
[27] Ye, R., Z. J. E. Liu, and M. Pathology, ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway. 2020. 113: p. 104350.
[28] Ferrario, C. M., et al., Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. 2005. 111 (20): p. 2605-2610.
[29] Solerte, S. B., et al., Sitagliptin treatment at the time of hospitalization was associated with reduced mortality in patients with type 2 diabetes and COVID-19: a multicenter, case-control, retrospective, observational study. Diabetes Care, 2020. 43 (12): p. 2999-3006.
[30] Israelsen, S. B., et al., Comparable COVID-19 outcomes with current use of GLP-1 receptor agonists, DPP-4 inhibitors or SGLT-2 inhibitors among patients with diabetes who tested positive for SARS-COV2. Diabetes, Obesity and Metabolism.
Author Information
  • Department of Endocrinology, First Affiliated Hospital of Xian Jiaotong University, Xi’an, China

  • Department of Endocrinology, First Affiliated Hospital of Xian Jiaotong University, Xi’an, China

  • Center for Advanced Studies in Vaccinology and Biotechnology, Balochistan Quetta, Pakistan

  • Department of Endocrinology, First Affiliated Hospital of Xian Jiaotong University, Xi’an, China

  • Department of Cardiology, First Affiliated Hospital, Xian Jiaotong University, Xi’an, China

  • Department of Cardiology, First Affiliated Hospital, Xian Jiaotong University, Xi’an, China

  • Department of Medicine, Northwest General Hospital, Peshawar, Pakistan

  • Department of Radiology, Second Affiliated Hospital, Xian Jiaotong University, Xi’an, China

  • Department of Radiology, Second Affiliated Hospital, Xian Jiaotong University, Xi’an, China

  • Internal Medicine, Westside Regional Medical Center, Plantation, USA

  • Internal Medicine, Saidu Hospital, Swat, Pakistan

  • Internal Medicine, Wah Medical Hospital, Wah Cantonment, Pakistan

  • Balochistan Institute of Nephrology and Urology Quetta, Quetta, Pakistan

  • Department of Endocrinology, First Affiliated Hospital of Xian Jiaotong University, Xi’an, China

Cite This Article
  • APA Style

    Hamad Haider Khan, Hui Guo, Safiullah Khan Achakzai, Yang Zhao, Hameed Ullah, et al. (2021). Review: COVID-19 Outbreak and Diabetic Patient’s Treatments Close Relationship. American Journal of Nursing Science, 10(6), 244-247. https://doi.org/10.11648/j.ajns.20211006.11

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    ACS Style

    Hamad Haider Khan; Hui Guo; Safiullah Khan Achakzai; Yang Zhao; Hameed Ullah, et al. Review: COVID-19 Outbreak and Diabetic Patient’s Treatments Close Relationship. Am. J. Nurs. Sci. 2021, 10(6), 244-247. doi: 10.11648/j.ajns.20211006.11

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    AMA Style

    Hamad Haider Khan, Hui Guo, Safiullah Khan Achakzai, Yang Zhao, Hameed Ullah, et al. Review: COVID-19 Outbreak and Diabetic Patient’s Treatments Close Relationship. Am J Nurs Sci. 2021;10(6):244-247. doi: 10.11648/j.ajns.20211006.11

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  • @article{10.11648/j.ajns.20211006.11,
      author = {Hamad Haider Khan and Hui Guo and Safiullah Khan Achakzai and Yang Zhao and Hameed Ullah and Shida Hussain and Shahzad Ahmad and Zahid Nadeem and Umair Ahmad and Khan Alam and Nawab Ali and Ayesha Jamil and Mirwais Khan and Bingyin Shi},
      title = {Review: COVID-19 Outbreak and Diabetic Patient’s Treatments Close Relationship},
      journal = {American Journal of Nursing Science},
      volume = {10},
      number = {6},
      pages = {244-247},
      doi = {10.11648/j.ajns.20211006.11},
      url = {https://doi.org/10.11648/j.ajns.20211006.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajns.20211006.11},
      abstract = {The severe acute respiratory syndrome (SARS-COV) are well known viruses from the family of Coronaviridae which in past caused outbreaks that led to various detrimental effect on world in many aspects. In the year 2019 when the new strain of coronavirus family (SARS-COV2) which is now known as COVID-19 (corona virus disease and 19 refer to the year it was first recognized) outbreak occurred in Wuhan affected the globe seriously. The health system got into a big challenge as this new strain of coronavirus spread much rapidly and caused much more mortality than the previous ones. The mortality was higher in those population which had comorbid conditions such as cardiovascular disease, lung disorders, chronic illnesses, diabetic patients and at the same time affected by COVID-19. Various regimes were selected but still proper and effective management is not available for such patients as these patients are already on multiple drugs. Among those chronic illnesses diabetic patients were found be highly susceptible to COVID-19. High disease mortality and worse outcomes in patients with diabetes urges that Diabetes appropriate management and better selection of drugs is crucial for the better outcomes in diabetic patients as most of the patients are treated for hypertension, hyperglycaemia and ongoing other chronic illnesses which could lead to worse case scenarios.},
     year = {2021}
    }
    

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    AU  - Hui Guo
    AU  - Safiullah Khan Achakzai
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    AB  - The severe acute respiratory syndrome (SARS-COV) are well known viruses from the family of Coronaviridae which in past caused outbreaks that led to various detrimental effect on world in many aspects. In the year 2019 when the new strain of coronavirus family (SARS-COV2) which is now known as COVID-19 (corona virus disease and 19 refer to the year it was first recognized) outbreak occurred in Wuhan affected the globe seriously. The health system got into a big challenge as this new strain of coronavirus spread much rapidly and caused much more mortality than the previous ones. The mortality was higher in those population which had comorbid conditions such as cardiovascular disease, lung disorders, chronic illnesses, diabetic patients and at the same time affected by COVID-19. Various regimes were selected but still proper and effective management is not available for such patients as these patients are already on multiple drugs. Among those chronic illnesses diabetic patients were found be highly susceptible to COVID-19. High disease mortality and worse outcomes in patients with diabetes urges that Diabetes appropriate management and better selection of drugs is crucial for the better outcomes in diabetic patients as most of the patients are treated for hypertension, hyperglycaemia and ongoing other chronic illnesses which could lead to worse case scenarios.
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