Review ArticleAn enlightening role for cytokine storm in coronavirus infection
Keywords
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Inflammatory cytokines
Coronavirus disease 2019 (COVID-19)
Multiple organ dysfunctions
Cytokine storm
Abbreviations
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
CoV
coronavirus
WHO
World Health Organization
ALI
acute lung injury
ARDS
acute respiratory distress syndrome
CNS
central nervous system
COVID-19
coronavirus disease 2019
MERS
Middle East respiratory syndrome
SARS
severe acute respiratory syndrome
IL
interleukin
IFN
interferons
TNF
tumor necrosis factor
MCP
monocyte chemoattractant protein
IL-1RA
IL-1 receptor antagonist
IP-10
IFN-γ-inducible protein-10
Th
helper T cell
DC
dendritic cell
NK
natural killer cell
B
B lymphocyte
Th2
T-helper-2 cell
BMSC
bone marrow stromal cell
Th1
T-helper-1 cell
PBMC
peripheral blood mononuclear cell
CCL
chemokine ligand
CXCL
chemokine (C-X-C motif) ligand
GCSF
granulocyte colony stimulating factor
GMCSF
granulocyte-macrophage colony-stimulating factor
FGF
fibroblast growth factor
PDGF
platelet derived growth factor
VEGF
vascular endothelial cell growth factor
MIP1A
macrophage Inflammatory Protein 1 Alpha
MIP1B
macrophage Inflammatory Protein 1 beta
PRRs
pattern recognition receptors
TLRs
Toll-like receptors
PAMPs
pathogen-associated molecular patterns
CRP
C-reactive protein
NLR
neutrophil-to-lymphocyte ratio
COVID-CSS
COVID-19 related cytokine storm syndrome
ACE2
angiotensin-converting enzyme 2
NF-κB
nuclear factor κB
JAK
Janus kinase
STAT
signal transducer and activator of transcription
IRF3
IFN regulatory factor-3
Cited by (0)
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First author: Zhongyi Zhao, Email: [email protected]
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