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Born into an Isolating World: Family-Centred Care for Babies Born to Mothers with COVID-19 the Epicentre Multinational Cohort Study

36 Pages Posted: 3 Oct 2022

See all articles by Georgie Dowse

Georgie Dowse

University of Melbourne - Neonatal Research

Elizabeth Perkins

University of Melbourne - Neonatal Research

Howard Stein

Promedica Ebied Children’s Hospital - Department of Pediatrics

Giovanna Chidini

University of Paris-Saclay - Division of Pediatrics and Neonatal Critical Care

Olivier Danhaive

Catholic University of Louvain (UCL) - Division of Neonatology (Pediatrics)

Yasser N. Elsayed

University of Manitoba - Department of Pediatrics & Child Health

Werther Brunow de Carvalho

University of São Paulo (USP) - Pediatric Intensive Care/Neonatology of the Department of Pediatrics

Niran Al-Naqeeb

Neonatal Department, AL-Adan Hospital

Shancy Rooze

Hôpital Universitaire des enfants Reine Fabiola - Unités de soins intensifs

Merih Cetinkaya

Basaksehir Cam and Sakura City Hospital - Department of Neonatology

Susanne Vetter-Laracy

Health Research Institute of the Balearic Islands (IdISBa)

Francisco Javier Pilar-Orive

Cruces University Hospital - Biocruces Bizkaia Health Research Institute

Paul Torpiano

Mater Dei Hospital - Department of Paediatrics and Adolescent Health

Walusa Assad Gonçalves-Ferri

University of São Paulo (USP) - Ribeirão Preto Medical School

Danilo Buonsenso

Fondazione Policlinico Universitario A. Gemelli IRCCS - Department of Woman and Child Health and Public Health

Bjarte Rogdo

Children’s Hospital of Eastern Switzerland - NICU/PICU

Alberto Medina

Hospital Central de Asturias - Pediatric Intensive Care Unit

Angelo Polito

University of Geneva - Department of Gynecology Obstetrics

Carole Brouwer

Leiden University - Pediatric Intensive Care Unit

Martin Kneyber

Beatrix Children’s Hospital - Division of Paediatric Critical Care Medicine

Daniele De Luca

University of Paris - Division of Pediatrics and Neonatal Critical Care

David Tingay

University of Melbourne - Neonatal Research

More...

Abstract

Background: The benefits of family-centred care (FCC) in the perinatal period for both mothers and babies are well-established. The aim of this study was to determine how the delivery of FCC practices were impacted for neonates born to mothers with perinatal SARS-CoV-2 infection during the COVID-19 pandemic.

Methods: Neonates born to mothers with confirmed SARS-CoV-2 infection during pregnancy were identified from the ‘EsPnIC Covid paEdiatric NeonaTal REgistry’ (EPICENTRE) multinational cohort between 10 March 2020 and 20 October 2021. The EPICENTRE cohort collected prospective data on FCC practices. Rooming-in and breastmilk feeding practice were the main outcomes, and factors influencing each were determined. Other outcomes included mother-baby physical contact prior to separation and the pattern of FCC components relative to time and local site guidelines.

Findings: 692 mother-baby dyads (13 sites, 10 countries) were analysed. 27 (5%) neonates were positive for SARS-CoV-2 (14 (52%) asymptomatic). Most sites had policies that encouraged FCC during perinatal SARS-CoV-2 infection for most of the reporting period. 311 (46%) neonates roomed-in with their mother during the admission. Rooming-in increased over time from 23% in Spring 2020 to 74% in Winter 2020/21. 330 (93%) of the 369 separated neonates had no FCC physical contact with their mother prior, and 319 (86%) were asymptomatic. Maternal breastmilk was used for feeding in 354 (53%) neonates, increasing from 23% to 70% between Spring 2020 and Winter 2020/21. FCC was most impacted when mothers had symptomatic COVID-19 at birth.

Interpretation: This is the largest report of global FCC practice during the COVID-19 pandemic to date. The COVID-19 pandemic has impacted FCC despite low perinatal transmission rates. Fortunately, clinicians appear to have adapted to allow more FCC delivery as the COVID-19 pandemic progressed.

Funding: This project is supported by the Victorian Government Operational Infrastructure
Support Program (Melbourne, Australia). DGT is supported by a National Health and Medical
Research Council (Australia) Investigator (Grant ID 2008212)

Declaration of Interest: : The other authors have no competing interests to declare.

Ethical Approval: The study was approved by the Human Research and Ethics Committee of the Royal Children’s Hospital, Melbourne, Australia on 11 May 2020 (HREC 64264) in accordance with National Health and Medical Research Council guidelines and is reported as per STROBE guidelines.

Keywords: breastfeeding, breastmilk, COVID-19, family-centred care, mother-baby contact, pandemic, perinatal care, rooming-in, SARS-CoV-2, skin-to-skin care

Suggested Citation

Dowse, Georgie and Perkins, Elizabeth and Stein, Howard and Chidini, Giovanna and Danhaive, Olivier and Elsayed, Yasser N. and de Carvalho, Werther Brunow and Al-Naqeeb, Niran and Rooze, Shancy and Cetinkaya, Merih and Vetter-Laracy, Susanne and Pilar-Orive, Francisco Javier and Torpiano, Paul and Gonçalves-Ferri, Walusa Assad and Buonsenso, Danilo and Rogdo, Bjarte and Medina, Alberto and Polito, Angelo and Brouwer, Carole and Kneyber, Martin and De Luca, Daniele and Tingay, David, Born into an Isolating World: Family-Centred Care for Babies Born to Mothers with COVID-19 the Epicentre Multinational Cohort Study. Available at SSRN: https://ssrn.com/abstract=4236441 or http://dx.doi.org/10.2139/ssrn.4236441

Georgie Dowse

University of Melbourne - Neonatal Research ( email )

Elizabeth Perkins

University of Melbourne - Neonatal Research ( email )

Howard Stein

Promedica Ebied Children’s Hospital - Department of Pediatrics ( email )

Giovanna Chidini

University of Paris-Saclay - Division of Pediatrics and Neonatal Critical Care ( email )

Olivier Danhaive

Catholic University of Louvain (UCL) - Division of Neonatology (Pediatrics) ( email )

Yasser N. Elsayed

University of Manitoba - Department of Pediatrics & Child Health ( email )

Werther Brunow De Carvalho

University of São Paulo (USP) - Pediatric Intensive Care/Neonatology of the Department of Pediatrics ( email )

Niran Al-Naqeeb

Neonatal Department, AL-Adan Hospital ( email )

Shancy Rooze

Hôpital Universitaire des enfants Reine Fabiola - Unités de soins intensifs ( email )

Merih Cetinkaya

Basaksehir Cam and Sakura City Hospital - Department of Neonatology ( email )

Susanne Vetter-Laracy

Health Research Institute of the Balearic Islands (IdISBa) ( email )

Francisco Javier Pilar-Orive

Cruces University Hospital - Biocruces Bizkaia Health Research Institute

Paul Torpiano

Mater Dei Hospital - Department of Paediatrics and Adolescent Health ( email )

Walusa Assad Gonçalves-Ferri

University of São Paulo (USP) - Ribeirão Preto Medical School

Danilo Buonsenso

Fondazione Policlinico Universitario A. Gemelli IRCCS - Department of Woman and Child Health and Public Health ( email )

Rome
Italy

Bjarte Rogdo

Children’s Hospital of Eastern Switzerland - NICU/PICU ( email )

Alberto Medina

Hospital Central de Asturias - Pediatric Intensive Care Unit ( email )

Angelo Polito

University of Geneva - Department of Gynecology Obstetrics ( email )

Carole Brouwer

Leiden University - Pediatric Intensive Care Unit ( email )

Martin Kneyber

Beatrix Children’s Hospital - Division of Paediatric Critical Care Medicine ( email )

Daniele De Luca

University of Paris - Division of Pediatrics and Neonatal Critical Care ( email )

France

David Tingay (Contact Author)

University of Melbourne - Neonatal Research

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