Coronary artery calcium score as a prognostic factor of adverse outcomes in patients with COVID-19: a comprehensive review

https://doi.org/10.1016/j.cpcardiol.2022.101175Get rights and content

Abstract

Background and aim: The association of known cardiovascular risk factors and poor prognosis of coronavirus disease 2019 (COVID-19) has been recently emphasized. Coronary artery calcium (CAC) score is considered to be a risk predictor of cardiovascular events. Therefore, we have conducted a review of literature on the predictive value of CAC score predictive value in COVID-19 outcome. Method: A search of literature was conducted, aiming for articles published until December 2021 on PubMed and Scopus to identify potentially eligible studies. Discussion: A total of 18 articles were reviewed for association between higher CAC score and adverse outcomes in COVID-19. Conclusion: The coronary calcium score could be considered as a new radiological marker for risk assessment in COVID-19 patients and providing additional information in fields of prognosis and possible cardiovascular complications. High CAC score is associated with higher in-hospital death and adverse clinical outcomes in patients with confirmed COVID-19, which highlights the importance of calcium load testing for hospitalized COVID-19 patients and calls for attention to patients with high CAC scores.

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The authors of this manuscript have no conflicts of interest to disclose. The authors declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

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