Original ArticleAlimentary TractProton Pump Inhibitor Use Is Not Strongly Associated With SARS-CoV-2 Related Outcomes: A Nationwide Study and Meta-analysis
Alimentary Tract
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open access
Graphical abstract
Keywords
PPI
COVID-19
Risk of Infection
Mortality
Abbreviations used in this paper
CI
confidence interval
COVID-19
coronavirus disease 2019
ICU
intensive care unit
NSAID
nonsteroidal anti-inflammatory drug
OR
odds ratio
PPI
proton pump inhibitor
RR
relative risk
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
SMD
standardized mean difference
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Conflicts of interest This author discloses the following: Thomas Benfield reports grants from Novo Nordisk Foundation, grants from Simonsen Foundation, grants and personal fees from GSK, grants and personal fees from Pfizer, personal fees from Boehringer Ingelheim, grants and personal fees from Gilead, personal fees from MSD, grants from Lundbeck Foundation, grants from Kai Hansen Foundation, and personal fees from Pentabase A/S, with no relation to the work reported in this article. The remaining authors disclose no conflicts.
Funding Supported by a grant from Erik and Susanna Olesen’s Charitable Fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© 2021 by the AGA Institute. Published by Elsevier Inc.