Elsevier

Journal of Materials Research and Technology

Volume 15, November–December 2021, Pages 2102-2116
Journal of Materials Research and Technology

Original Article
Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic

https://doi.org/10.1016/j.jmrt.2021.09.020Get rights and content
Under a Creative Commons license
open access

Abstract

Microorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high requirement and demand for the development of safety products finished with antimicrobial properties. The study involves the antimicrobial activity of natural cotton coated with copper iodide capped with Hibiscus rosa-sinensis L. flower extract (CuI-FE) which is rich in anthocyanin, cyanidin-3-sophoroside by ultrasonication method. The coated and uncoated cotton fabric was characterised through XRD, SEM, AFM, tensile strength and UV–Visible spectroscopic techniques. XRD confirmed the formation of CuI particles, SEM showed that CuI-FE was prismatic in shape. The average size of CuI-FE particles was found to be 552.45 nm. Anti-bacterial studies showed copper iodide particles to be a potent antimicrobial agent. AFM images confirmed the rupture of bacterial cell walls in the presence of prismatic CuI-FE. In-vitro cytotoxicity investigation of CuI-FE was performed against cancer and spleen cell lines to evaluate the cell viability. Cytotoxicity analysis revealed the IC50 value of 233.93 μg/mL in the presence of CuI-FE. Molecular docking study was also carried out to understand the interaction of CuI-FE with COVID-19 main protease. This paper has given an insight on the usage of CuI-FE coated on the cotton fabric that has proved to have strong inhibition against the nano ranged bacterial, cancerous cell line and a strong interaction with the COVID-19 protease. Such eco-friendly material will provide a safe environment even after the disposable of medical waste from the infectious diseases like influenza and current pandemic like COVID-19.

Keywords

Green synthesis
Cyanidin-3-sophoroside
CuI
Cotton fabric
Covid-19 main protease

Abbreviations

COVID-19
Corona Virus Disease – 2019
PPE
Personal Protective Equipment
FE
Hibiscus rosa-sinensis L. flower extract
CuI-FE
Copper iodide synthesized using Hibiscus rosa-sinensis L. flower extract
E. coli
Escherichia coli
S. faecalis
Streptococcus faecalis
EAC
Ehrlich Ascites Carcinoma
DLA
Dalton's Lymphoma Ascites
PBS
Phosphate buffered saline
RPMI Medium
Roswell Park Memorial Institute Medium
ROS
Reactive Oxygen Species

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