An overview of treatment options for COVID-19

Authors

  • Madhusmita Mohanty Mohapatra Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India
  • Manju Rajaram Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India
  • Dharm Prakash Dwivedi Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India
  • Vishnukant Govindraj Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India
  • Pratap Upadhya Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20204509

Keywords:

Antivirals, Convalescent plasma therapy, COVID-19, Immunosuppressant, Mesenchymal cell

Abstract

Severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) which emerged in Wuhan initially as pneumonia of unknown origin in December 2019, later spread to whole world and became pandemic on 11th March, 2020. Many drugs have been proposed but are backed without clinical evidence. Scientific bodies are in the row to discover a reliable vaccine and effective drugs against the novel coronavirus. Many antiviral and anti-parasitic drugs which were thought to have some effect on Coronavirus disease 2019 (COVID-19) have been tried during the crisis but none have shown concrete evidence of action. Randomized clinical trials on the repurposed drugs are now registered under clinical trial registry to look at the safety profile and efficacy of the drugs to be used against SARS-CoV-2. Many meta-analyses are being conducted worldwide to frame evidence for the fight against this novel coronavirus. We are providing below a review of various drugs that have been tried for treatment of COVID-19 as well as different clinical trials which are underway.

Author Biographies

Madhusmita Mohanty Mohapatra, Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India

Associate Professor, Department of Pulmonary Medicine, JIPMER

Manju Rajaram, Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India

Additional Professor, Departemnt of Pulmonary Medicine,JIPMER

Pratap Upadhya, Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India

Assistant Professor, Department of Pulmonary Medicine , JIPMER

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Published

2020-10-21

How to Cite

Mohapatra, M. M., Rajaram, M., Dwivedi, D. P., Govindraj, V., & Upadhya, P. (2020). An overview of treatment options for COVID-19. International Journal of Basic & Clinical Pharmacology, 9(11), 1770–1777. https://doi.org/10.18203/2319-2003.ijbcp20204509

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Section

Review Articles