Variations of COVID-19 Mortality Are Affected by Economic Disparities Across Countries
23 Pages Posted: 12 Jan 2022
Abstract
Background: When the COVID-19 case number reaches a maximum in a country, its capacity and management of health system face greatest challenge.
Methods: Using data reported by Worldometers and WHO Coronavirus (COVID-19) Dashboard, we compared the case fatality rates (CFRs) and time lags (in unit of day) between the turning points of cases and deaths among countries in different development stages and potential influence factors.
Findings: As of May 10, 2021, 106 out of 222 countries or regions (56%) reported more than 5,000 cases. Approximately half of them have experienced all the three waves of COVID-19 disease. The average mortality rate at the disease turning point was 0.038 for the first wave, 0.020 for the second wave, and 0.023 for wave 3. In high-income countries, the mortality rates during the first wave are higher than that of the other income levels. However, the mortality rates during the second and third waves of COVID-19 were much lower than those of the first wave, with a significant reduction from 5.7% to 1.7% approximately 70%. At the same time, high-income countries exhibited a 2-fold increase in time lags during the second and the third waves compared to the first wave. High rates in the first wave in developed countries are associated to multiple factors. In upper middle- and lower middle-income countries, the decreasing of mortality rates in the second and third waves were subtle or even reversed. In the upper and lower middle-income countries, the time lags were about 50% of the durations observed from high-income countries.
Interpretation: Economy and medical resources affect the efficiency of COVID-19 mitigation and the clinical outcomes of the patients. The situation is likely to become even worse in the light of these countries’ limited ability to combat COVID-19 as the new variant transmission becomes dominant.
Note:
Funding: This work was partially supported by funding from University of Tennessee Health Science Center (R073290109) to WG in Memphis, TN, USA, and grant 90DDUC0058 to CG from the U.S. Department of Health and Human Services, Administration for Community Living.
Declaration of Interests: We declare no competing interests.
Keywords: COVID-19, Economy, Income levels, Mortality, Waves, Turning points
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