Öz
SARS-CoV-2’nin neden olduğu COVID-19’da değişim ve/veya harabiyet tablolarına her geçen gün yenileri eklenmektedir. Birçok hücreyi enfekte edebilen bu virüsün ter bezi Krt7+ salgı lümen hücrelerini de kolayca enfekte edebildiği gösterilmiştir. Uçucu organik bileşikler ise birçok hastalık için biyomarker olup çeşitli hastalık ve sendromlarla ilişkilendirilmiştir. SARS-CoV-2’nin ter salgısını değiştirebileceği ve yarattığı tahribatlarla uçucu organik bileşikler ortaya çıkarabileceği gösterilmiştir. Bu yazımızda SARS-CoV-2 ile enfekte olan hastada, enfeksiyon esnasında gelişen ter kokusu değişimi sunulmuştur.
Anahtar Kelimeler
Kaynakça
- Liu J, Li Y, Liu L, Hu X, Wang X, Hu H, et al. Infection of human sweat glands by SARS-CoV-2. Cell Discov. 2020;6:84.
- Schmidt K, Podmore I. Current Challenges in Volatile Organic Compounds Analysis as Potential Biomarkers of Cancer. J Biomark. 2015;2015:981458.
- Sakr R, Ghsoub C, Rbeiz C, Lattouf V, Riachy R, Haddad C, et al. COVID-19 detection by dogs: from physiology to field application—a review article. Postgraduate Medical Journal. 2021. p. ostgradmedj–2020. doi:10.1136/postgradmedj-2020-139410
- Harker M. Psychological sweating: a systematic review focused on aetiology and cutaneous response. Skin Pharmacol Physiol. 2013;26:92–100.
- Semkova K, Gergovska M, Kazandjieva J, Tsankov N. Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. Clin Dermatol. 2015;33:483–491.
- Hung R, Lee S, Bennett JW. Fungal volatile organic compounds and their role in ecosystems. Appl Microbiol Biotechnol. 2015;99:3395–3405.
- Amann A, Costello B de L, Miekisch W, Schubert J, Buszewski B, Pleil J, et al. The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva. J Breath Res. 2014;8:034001.
- Besa V, Teschler H, Kurth I, Khan AM, Zarogoulidis P, Baumbach JI, et al. Exhaled volatile organic compounds discriminate patients with chronic obstructive pulmonary disease from healthy subjects. Int J Chron Obstruct Pulmon Dis. 2015;10:399–406.
- Lamote K, Janssens E, Schillebeeckx E, Lapperre TS, De Winter BY, van Meerbeeck JP. The scent of COVID-19: viral (semi-)volatiles as fast diagnostic biomarkers? J Breath Res. 2020;14:042001.
- Grandjean D, Sarkis R, Lecoq-Julien C, Benard A, Roger V, Levesque E, et al. Can the detection dog alert on COVID-19 positive persons by sniffing axillary sweat samples? A proof-of-concept study. PLoS One. 2020;15:e0243122.
Öz
New ones are added to the manifestations of change and/or destruction in COVID-19 caused by SARS-CoV-2 every day. It has been shown that this virus, which can infect many cells, can also easily infect sweat gland Krt7+ secretory lumen cells. Volatile organic compounds are biomarkers for many diseases and have been associated with various diseases and syndromes. It has been shown that SARS-CoV-2 can change sweat secretion and produce volatile organic compounds with the damage it causes. In this article, the change in odor of sweat that developed during the infection in a patient infected with SARS-CoV-2 is presented.
Anahtar Kelimeler
Kaynakça
- Liu J, Li Y, Liu L, Hu X, Wang X, Hu H, et al. Infection of human sweat glands by SARS-CoV-2. Cell Discov. 2020;6:84.
- Schmidt K, Podmore I. Current Challenges in Volatile Organic Compounds Analysis as Potential Biomarkers of Cancer. J Biomark. 2015;2015:981458.
- Sakr R, Ghsoub C, Rbeiz C, Lattouf V, Riachy R, Haddad C, et al. COVID-19 detection by dogs: from physiology to field application—a review article. Postgraduate Medical Journal. 2021. p. ostgradmedj–2020. doi:10.1136/postgradmedj-2020-139410
- Harker M. Psychological sweating: a systematic review focused on aetiology and cutaneous response. Skin Pharmacol Physiol. 2013;26:92–100.
- Semkova K, Gergovska M, Kazandjieva J, Tsankov N. Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. Clin Dermatol. 2015;33:483–491.
- Hung R, Lee S, Bennett JW. Fungal volatile organic compounds and their role in ecosystems. Appl Microbiol Biotechnol. 2015;99:3395–3405.
- Amann A, Costello B de L, Miekisch W, Schubert J, Buszewski B, Pleil J, et al. The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva. J Breath Res. 2014;8:034001.
- Besa V, Teschler H, Kurth I, Khan AM, Zarogoulidis P, Baumbach JI, et al. Exhaled volatile organic compounds discriminate patients with chronic obstructive pulmonary disease from healthy subjects. Int J Chron Obstruct Pulmon Dis. 2015;10:399–406.
- Lamote K, Janssens E, Schillebeeckx E, Lapperre TS, De Winter BY, van Meerbeeck JP. The scent of COVID-19: viral (semi-)volatiles as fast diagnostic biomarkers? J Breath Res. 2020;14:042001.
- Grandjean D, Sarkis R, Lecoq-Julien C, Benard A, Roger V, Levesque E, et al. Can the detection dog alert on COVID-19 positive persons by sniffing axillary sweat samples? A proof-of-concept study. PLoS One. 2020;15:e0243122.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Bulaşıcı Hastalıklar |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2021 |
| Kabul Tarihi | 8 Kasım 2021 |
| Yayımlandığı Sayı | Yıl 2021 Cilt: 5 Sayı: 3 |
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